Antibodies can impact pathogens in the presence or in the absence of effector cells or
effector molecules such as complement, and experiments can often sort out with precision …

Candidiasis is an infection caused by fungi from a Candida species, most commonly
Candida albicans. C. albicans is an opportunistic fungal pathogen typically residing on …

Invasive fungal infections are increasing in incidence and are associated with substantial
mortality. Improved diagnostics and the availability of new antifungals have revolutionized …

Cryptococcal meningitis is a devastating brain infection cause by encapsulated yeasts of the
Cryptococcus genus. Exposure, through inhalation, is likely universal by adulthood, but …

While the incidence of cryptococccal meningitis in the developed world has declined with
widespread, early antiretroviral therapy (ART), cryptococcal disease remains a major …

Abstract Background. Mycograb (Neu Tec Pharma) is a human recombinant monoclonal
antibody against heat shock protein 90 that, in laboratory studies, was revealed to have …

Nations' ongoing struggles with a number of novel and reemerging infectious diseases,
including the ongoing global health issue, the SARS-Co-V2 (severe acute respiratory …

Cryptococcosis is an important opportunistic infection and a leading cause of meningitis in
patients with HIV infection. The antifungal pharmacological treatment is limited to …

In patients with hematologic malignancies due to immune system disorders, especially
persistent febrile neutropenia, invasive fungal infections (IFI) occur with high mortality …

Half a century after the introduction of Amphotericin B the management of cryptococcosis
remains unsatisfactory. The disease, caused primarily by the two fungal species …