Chondroitin Sulfate: Emerging biomaterial for biopharmaceutical purpose and tissue engineering

R Sharma, K Kuche, P Thakor, V Bhavana… - Carbohydrate …, 2022 - Elsevier
Chondroitin Sulfate (CS) is an anionic hetero polysaccharide possessing anti-inflammatory,
antioxidant, antitumor, anticoagulant and antithrombogenic activities. It is biodegradable and …

Nanoparticle–cartilage interaction: pathology-based intra-articular drug delivery for osteoarthritis therapy

X Li, B Dai, J Guo, L Zheng, Q Guo, J Peng, J Xu… - Nano-micro letters, 2021 - Springer
Osteoarthritis is the most prevalent chronic and debilitating joint disease, resulting in huge
medical and socioeconomic burdens. Intra-articular administration of agents is clinically …

Natural polymers: polysaccharides and their derivatives for biomedical applications

A Aravamudhan, DM Ramos, AA Nada… - Natural and synthetic …, 2014 - Elsevier
Several polymers of both natural and synthetic origin have been used for a variety of
biomedical applications including pharmaceutical preparations, drug targeting, imaging …

Natural polysaccharides: Chemical properties and application in pharmaceutical formulations

M Tudu, A Samanta - European Polymer Journal, 2023 - Elsevier
Natural polysaccharides have an important role in pharmaceutical industries and are
considered a huge source and importance. Polysaccharides are biopolymers characterized …

Medical application of glycosaminoglycans: a review

A Köwitsch, G Zhou, T Groth - Journal of tissue engineering …, 2018 - Wiley Online Library
The characteristic molecular composition of the different glycosaminoglycans (GAGs) is
related to their role as structural components and regulators of a multitude of functions of …

Polysaccharide-based conjugates for biomedical applications

A Basu, KR Kunduru, E Abtew, AJ Domb - Bioconjugate chemistry, 2015 - ACS Publications
Polysaccharides contain different functional groups (such as hydroxyl, amino, carboxylic
acid, aldehydes) that make them ideal for conjugation. They are biodegradable …

Chondroitin sulphate: a focus on osteoarthritis

M Bishnoi, A Jain, P Hurkat, SK Jain - Glycoconjugate journal, 2016 - Springer
Chondroitin sulfate (CS) being a natural glycosaminoglycan is found in the cartilage and
extracellular matrix. It shows clinical benefits in symptomatic osteoarthritis (OA) of the finger …

Chondroitin sulfate, hyaluronic acid and chitin/chitosan production using marine waste sources: Characteristics, applications and eco-friendly processes: A review

JA Vázquez, I Rodríguez-Amado, MI Montemayor… - Marine drugs, 2013 - mdpi.com
In the last decade, an increasing number of glycosaminoglycans (GAGs), chitin and chitosan
applications have been reported. Their commercial demands have been extended to …

Structural and mechanistic classification of uronic acid-containing polysaccharide lyases

ML Garron, M Cygler - Glycobiology, 2010 - academic.oup.com
Polysaccharide lyases (PLs) have been assigned to 21 families based on their sequences,
with~ 50 singletons awaiting further classification. For 19 of these families, the structure of at …

Biomaterials and tissue engineering approaches using glycosaminoglycans for tissue repair: Lessons learned from the native extracellular matrix

R Menezes, R Vincent, L Osorno, P Hu, TL Arinzeh - Acta biomaterialia, 2023 - Elsevier
Glycosaminoglycans (GAGs) are an important component of the extracellular matrix as they
influence cell behavior and have been sought for tissue regeneration, biomaterials, and …