[HTML][HTML] Enhancing translation: A need to leverage complex preclinical models of addictive drugs to accelerate substance use treatment options
C Corley, A Craig, S Sadek, JA Marusich… - Pharmacology …, 2024 - Elsevier
Preclinical models of addictive drugs have been developed for decades to model aspects of
the clinical experience in substance use disorders (SUDs). These include passive exposure …
the clinical experience in substance use disorders (SUDs). These include passive exposure …
Role of dorsal striatum circuits in relapse to opioid seeking after voluntary abstinence
High relapse rate during abstinence is a defining characteristic of drug addiction. We
previously found that opioid seeking progressively increases after voluntary abstinence …
previously found that opioid seeking progressively increases after voluntary abstinence …
Neuroplasticity-related genes correlate with individual differences in distinct phases of oxycodone self-administration in male rats
FM Vassoler, KE Budge, SB Isgate, KR Gildawie… - …, 2024 - Elsevier
Opioid use disorder (OUD) is a chronic condition associated with long-lasting molecular and
behavioral changes. Animals with prolonged access to opioids develop behaviors similar to …
behavioral changes. Animals with prolonged access to opioids develop behaviors similar to …