BACKGROUND Here we describe the consensus guideline methodology, summarise the
evidence-based recommendations we provided to the World Health Organisation (WHO) for …

Whilst many multiparous women are obese (body mass index O30 kg/m2), obesity has been
associated with impaired fecundity; however, the mechanism which links obesity to reduced …

Background Polycystic ovary syndrome (PCOS) is characterised by infrequent or absent
ovulation, and high levels of androgens and insulin (hyperinsulinaemia). Hyperinsulinaemia …

The majority of cellular and molecular andrologists endorse the view that the sperm is a
vessel for transporting the paternal genome to the waiting egg and nothing more. Any …

One in six couples have an unwanted delay in conception. Roughly half of these couples
will conceive either spontaneously or with relatively simple advice or treatment. The other …

With almost 50% of infertility attributed either wholly or in part to male issues, it has become
increasingly important to look at infertility from a couple's perspective. Advances in assisted …

Research on spermatozoal RNA has made considerable progress since the original reports
on its presence appeared in the late 1950s and early 1960s. Through the use of stringent …

Background Polycystic ovary syndrome (PCOS) is characterised by infrequent or absent
ovulation, and high levels of androgens and insulin (hyperinsulinaemia). Hyperinsulinaemia …

The narrow standard age range of menopause,∼ 50 yr, belies the complex balance of
forces that govern the underlying formation and progressive loss of ovarian follicles (the …

The mammalian ovarian reserve is comprised of a finite pool of primordial follicles,
representing the lifetime reproductive capacity of females. In most mammals, the reserve is …