Extracellular vesicles are released by the majority of cell types and circulate in body fluids.
They function as a long-distance cell-to-cell communication mechanism that modulates the …

Human mesenchymal stem cells (MSCs) have become a hot topic in the development of cell
therapies and bioengineering. All kinds of MSCs are genomic stable and have the self …

Sepsis is characterized as an uncontrolled host response to infection, and it represents a
serious health challenge, causing excess mortality and morbidity worldwide. The discovery …

Mesenchymal stem cells (MSCs) have become important seed cells in therapy because of
their immunosuppressive function and anti-inflammatory effects. MSCs exert …

Acute kidney injury (AKI) and chronic kidney disease (CKD) are rising in global prevalence
and cause significant morbidity for patients. Current treatments are limited to slowing instead …

With the ever-increasing burden of kidney disease, the need for developing new
therapeutics to manage this disease has never been greater. Extracellular vesicles (EVs) …

Burns are a seriously underestimated form of trauma that not only damage the skin system
but also cause various complications, such as acute kidney injury (AKI). Recent clinical …

Viral infections lead to the death of more than a million people each year around the world,
both directly and indirectly. Viruses interfere with many cell functions, particularly critical …

Background Sepsis is a debilitating systemic inflammation that resulted from infection or
injury. Despite many advances in treatment, the resulting mortality rate has remained high …

Abstract The role of microRNA-21-5p (miR-21-5p) in sepsis-induced acute kidney injury
(AKI) has been seldom discussed. Therefore, the objective of this present study was to …