Immune regulation through tryptophan metabolism
SK Seo, B Kwon - Experimental & Molecular Medicine, 2023 - nature.com
Amino acids are fundamental units of molecular components that are essential for sustaining
life; however, their metabolism is closely interconnected to the control systems of cell …
life; however, their metabolism is closely interconnected to the control systems of cell …
Strategies to overcome DC dysregulation in the tumor microenvironment
G Mestrallet, K Sone, N Bhardwaj - Frontiers in Immunology, 2022 - frontiersin.org
Dendritic cells (DCs) play a key role to modulate anti-cancer immunity in the tumor
microenvironment (TME). They link innate to adaptive immunity by processing and …
microenvironment (TME). They link innate to adaptive immunity by processing and …
SLC38A2 and glutamine signalling in cDC1s dictate anti-tumour immunity
C Guo, Z You, H Shi, Y Sun, X Du, G Palacios, C Guy… - Nature, 2023 - nature.com
Cancer cells evade T cell-mediated killing through tumour–immune interactions whose
mechanisms are not well understood,. Dendritic cells (DCs), especially type-1 conventional …
mechanisms are not well understood,. Dendritic cells (DCs), especially type-1 conventional …
Dubosiella newyorkensis modulates immune tolerance in colitis via the L-lysine-activated AhR-IDO1-Kyn pathway
Y Zhang, S Tu, X Ji, J Wu, J Meng, J Gao… - Nature …, 2024 - nature.com
Commensal bacteria generate immensely diverse active metabolites to maintain gut
homeostasis, however their fundamental role in establishing an immunotolerogenic …
homeostasis, however their fundamental role in establishing an immunotolerogenic …
Mature dendritic cells enriched in immunoregulatory molecules (mregDCs): a novel population in the tumour microenvironment and immunotherapy target
J Li, J Zhou, H Huang, J Jiang… - Clinical and …, 2023 - Wiley Online Library
Abstract Background Dendritic cells (DCs) mediate divergent immune effects by activating T
cells or negatively regulating the immune response to promote immune tolerance. They …
cells or negatively regulating the immune response to promote immune tolerance. They …
Role of Innate Immunity in Allergic Contact Dermatitis: An Update
HL Yamaguchi, Y Yamaguchi, E Peeva - International Journal of …, 2023 - mdpi.com
Our understanding of allergic contact dermatitis mechanisms has progressed over the past
decade. Innate immune cells that are involved in the pathogenesis of allergic contact …
decade. Innate immune cells that are involved in the pathogenesis of allergic contact …
Life and death of tolerogenic dendritic cells
J Bourque, D Hawiger - Trends in immunology, 2023 - cell.com
In contrast to conventional dendritic cells (cDCs) that are constantly exposed to microbial
signals at anatomical barriers, cDCs in systemic lymphoid organs are sheltered from …
signals at anatomical barriers, cDCs in systemic lymphoid organs are sheltered from …
Transcriptional regulation of dendritic cell development and function
Dendritic cells (DCs) are sentinel immune cells that form a critical bridge linking the innate
and adaptive immune systems. Extensive research addressing the cellular origin and …
and adaptive immune systems. Extensive research addressing the cellular origin and …
Notch-dependent cooperativity between myeloid lineages promotes Langerhans cell histiocytosis pathology
Langerhans cell histiocytosis (LCH) is a potentially fatal neoplasm characterized by the
aberrant differentiation of mononuclear phagocytes, driven by mitogen-activated protein …
aberrant differentiation of mononuclear phagocytes, driven by mitogen-activated protein …
Mechanism of TLR4-Mediated Anti-Inflammatory Response Induced by Exopolysaccharide from the Probiotic Bacillus subtilis
J Zamora-Pineda, O Kalinina, AI Sperling… - The Journal of …, 2023 - journals.aai.org
Intestinal inflammatory diseases affect millions of people worldwide, and one class of drugs
showing promise toward treatment of several inflammatory diseases is probiotics. Numerous …
showing promise toward treatment of several inflammatory diseases is probiotics. Numerous …