Function and therapeutic potential of G protein‐coupled receptors in epididymis

D Zhang, Y Wang, H Lin, Y Sun, M Wang… - British Journal of …, 2020 - Wiley Online Library
Infertility rates for both females and males have increased continuously in recent years.
Currently, effective treatments for male infertility with defined mechanisms or targets are still …

Formononetin attenuates atopic dermatitis by upregulating A20 expression via activation of G protein-coupled estrogen receptor

W Yuan, Y Chen, Y Zhou, K Bao, X Yu, Y Xu… - Journal of …, 2021 - Elsevier
Ethnopharmacological relevance Atopic dermatitis (AD) is a complex skin disease with
highly heterogeneous inflammation, which ranks among the largest component of the …

G protein-coupled estrogen receptor promotes acrosome reaction via regulation of Ca2+ signaling in mouse sperm

DD Gao, CF Lan, XN Cao, L Chen, TL Lei… - Biology of …, 2022 - academic.oup.com
G protein-coupled estrogen receptor (GPER), a seven-transmembrane G protein-coupled
receptor, mediates the rapid pre-genomic signaling actions of estrogen and derivatives …

G protein-coupled estrogen receptor (GPER) in adult boar testes, epididymis and spermatozoa during epididymal maturation

R Krejčířová, M Maňasová, V Sommerová… - International journal of …, 2018 - Elsevier
The G protein-coupled estrogen receptor (GPER) is a transmembrane receptor considered
as a mediator of rapid non-genomic responses. GPER has been found in the male …

Aerobic exercises regulate the epididymal anion homeostasis of high-fat diet-induced obese rats through TRPA1-mediated Cl and HCO3 secretion

DD Gao, N Ding, WJ Deng, PL Li, YL Chen… - Biology of …, 2023 - academic.oup.com
Aerobic exercises could improve the sperm motility of obese individuals. However, the
underlying mechanism has not been fully elucidated, especially the possible involvement of …

Pregnancy Achievement by Medical Assisted Reproduction Is Correlated to the G Protein-Coupled Receptor 30 mRNA Abundance in Human Spermatozoa

SC Pereira, IF Esperança, S Pinto, A Barros, M Sousa… - Applied Sciences, 2022 - mdpi.com
Estrogens, specifically 17β-estradiol (E2), play an important role in male health, including
male fertility. The G protein-coupled receptor for estrogen 30 (GPR30) is essential for …

G protein-coupled estrogen receptor promotes acrosome reaction via regulation of Ca2+ signaling in mouse sperm

G Dong-Dong, L Chong-Feng, XN Cao… - Biology of …, 2022 - search.proquest.com
G protein-coupled estrogen receptor (GPER), a seven-transmembrane G protein-coupled
receptor, mediates the rapid pre-genomic signaling actions of estrogen and derivatives …

Localization of estrogen receptors in male reproductive tissues and sperm cells-a review.

R Krejčířová, P Postlerová, R Rajmon - Scientia Agriculturae …, 2018 - cabdirect.org
The effect of endogenous estrogens on the male reproductive tissues and development of
gametes is an essential for the reproductive success. Estrogens affect the target cells via …

İnsan semeninde östrojen reseptörleri; Erkek infertilitesi ile ilişkisi

V Aydoğan - 2019 - acikerisim.selcuk.edu.tr
Özet İnfertil çiftlerin% 20-50'sinde infertilite erkek kaynaklıdır. Östrojenlerin erkek üreme
fonksiyonlarında önemli rolleri olduğu bilinmektedir. Östrojenler, erkek üreme sisteminde …