Neoadjuvant therapy for pancreatic cancer

C Springfeld, CR Ferrone, MHG Katz… - Nature Reviews …, 2023 - nature.com
Patients with localized pancreatic ductal adenocarcinoma (PDAC) are best treated with
surgical resection of the primary tumour and systemic chemotherapy, which provides …

Pancreatic cancer

JD Mizrahi, R Surana, JW Valle, RT Shroff - The Lancet, 2020 - thelancet.com
Pancreatic cancer is a highly fatal disease with a 5-year survival rate of approximately 10%
in the USA, and it is becoming an increasingly common cause of cancer mortality. Risk …

Neoadjuvant chemoradiotherapy versus upfront surgery for resectable and borderline resectable pancreatic cancer: long-term results of the Dutch randomized …

E Versteijne, JL van Dam, M Suker… - Journal of Clinical …, 2022 - ascopubs.org
PURPOSE The benefit of neoadjuvant chemoradiotherapy in resectable and borderline
resectable pancreatic cancer remains controversial. Initial results of the PREOPANC trial …

Pancreatic adenocarcinoma, version 2.2021, NCCN clinical practice guidelines in oncology

MA Tempero, MP Malafa, M Al-Hawary… - Journal of the National …, 2021 - jnccn.org
Pancreatic cancer is the fourth leading cause of cancer-related death among men and
women in the United States. A major challenge in treatment remains patients' advanced …

Optimizing the outcomes of pancreatic cancer surgery

O Strobel, J Neoptolemos, D Jaeger… - Nature reviews Clinical …, 2019 - nature.com
Pancreatic cancer is likely to become the second most frequent cause of cancer-associated
mortality within the next decade. Surgical resection with adjuvant systemic chemotherapy …

FOLFIRINOX or gemcitabine as adjuvant therapy for pancreatic cancer

T Conroy, P Hammel, M Hebbar… - … England Journal of …, 2018 - Mass Medical Soc
Background Among patients with metastatic pancreatic cancer, combination chemotherapy
with fluorouracil, leucovorin, irinotecan, and oxaliplatin (FOLFIRINOX) leads to longer …

Therapeutic developments in pancreatic cancer: current and future perspectives

JP Neoptolemos, J Kleeff, P Michl, E Costello… - Nature reviews …, 2018 - nature.com
The overall 5-year survival for pancreatic cancer has changed little over the past few
decades, and pancreatic cancer is predicted to be the second leading cause of cancer …

Pancreatic adenocarcinoma, version 2.2017, NCCN clinical practice guidelines in oncology

MA Tempero, MP Malafa, M Al-Hawary… - Journal of the National …, 2017 - jnccn.org
Ductal adenocarcinoma and its variants account for most pancreatic malignancies. High-
quality multiphase imaging can help to preoperatively distinguish between patients eligible …

NCCN guidelines insights: pancreatic adenocarcinoma, version 1.2019: featured updates to the NCCN guidelines

MA Tempero, MP Malafa, EG Chiorean, B Czito… - Journal of the National …, 2019 - jnccn.org
The NCCN Guidelines for Pancreatic Adenocarcinoma discuss the diagnosis and
management of adenocarcinomas of the exocrine pancreas and are intended to assist with …

Pancreatic ductal adenocarcinoma: current and evolving therapies

A Adamska, A Domenichini, M Falasca - International journal of molecular …, 2017 - mdpi.com
Pancreatic ductal adenocarcinoma (PDAC), which constitutes 90% of pancreatic cancers, is
the fourth leading cause of cancer-related deaths in the world. Due to the broad …