Human Genomic Loci Important in Common Infectious Diseases: Role of High‐Throughput Sequencing and Genome‐Wide Association Studies

G Mboowa, I Sserwadda, M Amujal… - Canadian Journal of …, 2018 - Wiley Online Library
HIV/AIDS, tuberculosis (TB), and malaria are 3 major global public health threats that
undermine development in many resource‐poor settings. Recently, the notion that positive …

[HTML][HTML] Investigating the role of gene-gene interactions in TB susceptibility

M Daya, L Van Der Merwe, PD Van Helden, M Möller… - PLoS …, 2015 - journals.plos.org
Tuberculosis (TB) is the second leading cause of mortality from infectious disease
worldwide. One of the factors involved in developing disease is the genetics of the host, yet …

[HTML][HTML] Cell differentiation degree as a factor determining the role for different T-helper populations in tuberculosis protection

I Lyadova, I Nikitina - Frontiers in Immunology, 2019 - frontiersin.org
Efficient tuberculosis (TB) control depends on early TB prediction and prevention. Solution to
these tasks requires knowledge of TB protection correlates (TB CoPs), ie, laboratory markers …

A genetic perspective on granulomatous diseases with an emphasis on mycobacterial infections

UI Wu, SM Holland - Seminars in immunopathology, 2016 - Springer
Identification of the genetic factors predisposing to mycobacterial infections has been a
subject of intense research activities. Current knowledge of the genetic and immunological …

Clinical relevance of the lnc‐HNF1B‐3: 1 genetic polymorphisms in Western Chinese tuberculosis patients

Q Wu, H Zhong, H Bai, T Liu, J Song… - Journal of Clinical …, 2020 - Wiley Online Library
Background Tuberculosis remains a global public health problem. Genetic polymorphisms
may affect the susceptibility, clinical characteristics, and adverse drug reactions of patients …

Human genetics of tuberculosis

J El Baghdadi, AV Grant, A Sabri, S El Azbaoui, H Zaidi… - 2013 - books.google.com
Tuberculosis (TB) remains a major public health problem, as Mycobacterium tuberculosis
infects about one third of the world's population, with> 9 million new cases and~ 1.5 million …

[HTML][HTML] Integrated sequence-based genomic, transcriptomic, and methylation characterization of the susceptibility to tuberculosis in monozygous twins

Z Liu, B Deligen, Z Han, C Gerile, A Da - Heliyon, 2024 - cell.com
Background Tuberculosis (TB) is a complex disease with a spectrum of outcomes for more
than six decades; however, the genomic and epigenetic mechanisms underlying the highly …

[HTML][HTML] Fine-mapping host genetic variation underlying outcomes to Mycobacterium bovis infection in dairy cows

S Wilkinson, SC Bishop, AR Allen, SH McBride… - BMC genomics, 2017 - Springer
Abstract Background Susceptibility to Mycobacterium bovis infection in cattle is governed in
part by host genetics. However, cattle diagnosed as infected with M. bovis display varying …

[HTML][HTML] CCR5 Promoter Polymorphisms Associated With Pulmonary Tuberculosis in a Chinese Han Population

S Liu, N Liu, H Wang, X Zhang, Y Yao… - Frontiers in …, 2021 - frontiersin.org
Background Tuberculosis (TB), an infectious disease caused by Mycobacterium
tuberculosis, is a major public health concern. Chemokines and their receptors, such as …

Primary subacute epiphyseal osteomyelitis caused by Mycobacterium species in young children: a modern diagnostic approach

N El Houmami, P Minodier, C Bouvier… - European Journal of …, 2017 - Springer
Primary epiphyseal subacute osteomyelitis (PESAO) caused by Mycobacterium species in
young children is poorly recognized. We aimed to define the spectrum of this uncommon …