Aging is a natural but relentless process of physiological decline, leading to physical frailty,
reduced ability to respond to physical stresses (resilience) and, ultimately, organismal death …

Background: Oral squamous cell carcinoma (OSCC) is one of the most frequent cancers
worldwide. Endoscopic methods may be useful in the evaluation of oral injuries even though …

Inflammation, especially chronic inflammation, is closely linked to tumor development. As
essential chronic inflammatory cytokines, the interleukin family plays a key role in …

Over recent decades, the field of cellular senescence has attracted considerable attention
due to its association with aging, the development of age-related diseases and cancer …

Decades ago, the study of cancer biology was mainly focused on the tumor itself, paying
little attention to the tumor microenvironment (TME). Currently, it is well recognized that the …

Senescent cells secrete inflammatory proteins and small extracellular vesicles (sEVs),
collectively termed senescence-associated secretory phenotype (SASP), and promote age …

The interleukin-1 receptor antagonist (IL-1Ra) is an anti-inflammatory cytokine and a
naturally occurring antagonist of the IL-1 receptor. It effectively counteracts the IL-1 signaling …

Cannabidiolic acid (CBDA) is the main precannabinoid in industrial hemp. It represents a
common constituent of hemp seed oil, but mainly abundant in the aerial parts of the plant …

Simple Summary The early treatment of oral cancer is a high priority, as improvements in
this area could lead to greater cure rates and reduced disability due to extensive surgery …

Different efforts have been made to find better and less invasive methods for the diagnosis
and prediction of oral cancer, such as the study of saliva as a source of biomarkers. The aim …