In this review, we focus on the potential role of the γ-aminobutyric acidergic (GABAergic)
system in age-related episodic memory impairments in humans, with a particular focus on …

γ-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the vertebrate brain.
In the past, there has been a major research drive focused on the dysfunction of the …

The Religious Orders Study is a longitudinal clinical-pathologic cohort study of aging and
Alzheimer's disease (AD). In this manuscript, we summarize the study methods including the …

Alzheimer's disease (AD) is characterized by the classical hallmarks of Aβ-deposition and
tau-pathology that are thought to ultimately lead to synapse and neuron loss. Although long …

The central nervous system, once thought to be a site of immunological privilege, has since
been found to harbour immunocompetent cells and to communicate with the peripheral …

γ-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter, playing a central role
in the regulation of cortical excitability and the maintenance of the excitatory/inhibitory (E/I) …

In this article we present a comprehensive review of relevant research and reports on the
GABAA receptor in the aged and Alzheimer's disease (AD) brain. In comparison to …

Gamma‐aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central
nervous system. GABA type A receptors (GABAAR s) are severely affected in Alzheimer's …

GABA is the major inhibitory neurotransmitter in the central nervous system (CNS). The type
A GABA receptor (GABAAR) system is the primary pharmacological target for many drugs …

The γ-aminobutyric acid (GABA) ergic system is the primary inhibitory neurotransmission
system in the mammalian brain. Its dysregulation has been shown in multiple brain …