The formation of new blood vessels, called angiogenesis, is an essential pathophysiological
process in which several families of regulators have been implicated. Among these, vascular …

The progression of cancer involves a critical step in which malignant cells escape from
control by the immune system. Antineoplastic agents are particularly efficient when they …

Cancer-associated fibroblasts (CAFs) are a heterogeneous cell population that plays a
crucial role in remodeling the tumor microenvironment (TME). Here, through the integrated …

Cancers undergo sequential changes to proton (H+) concentration and sensing that are
consequences of the disease and facilitate its further progression. The impact of protonation …

Cuproptosis is a newly identified form of cell death driven by copper. Recently, the role of
copper and copper triggered cell death in the pathogenesis of cancers have attracted …

Cervical cancer (CC) is a gynecological neoplasm with the highest incidence rate, primarily
attributed to the persistent infection of high-risk Human papillomavirus (HPV). Despite …

Ocular surface neovascularization and its resulting pathological changes significantly alter
corneal refraction and obstruct light path to the retina, and hence is a major cause of vision …

Targeting angiogenesis has remained one of the important aspects in disease biology in
general and cancer in particular. Currently (June 2023), over 593 clinical trials have been …

Cancer immunity is subject to spatiotemporal regulation by leukocyte interaction with the
tumor microenvironment. Growing evidence suggests an emerging role for the vasculature …

The effectiveness of various cancer therapies for solid tumors is substantially limited by the
highly hypoxic tumor microenvironment (TME). Here, a microalgae-integrated living …