Background: Scleroderma is a heterogeneous group of diseases that can be localized or
systemic. Localized scleroderma is a fibrosis of the skin characterized by inflammation and …

The clinical use of extracorporeal photopheresis (ECP) for accepted indications such as
graft-versus-host disease, transplant rejection, and cutaneous T-cell lymphoma continues to …

Systemic autoimmune diseases (AID) have multiorgan, heterogeneous clinical
presentations and are characterized by dysregulation of the immune system …

Abstract Purpose of Review Systemic sclerosis (SSc) is a life-threatening autoimmune
disease that causes debilitating skin fibrosis. The skin in SSc is easily accessible, and skin …

Systemic sclerosis is an extremely variable disease in its manifestations and consequently,
treatment needs to be individualized depending on the specific problems that each patient …

The immune system is tasked with the unique challenge of recognizing foreign pathogens
and damaged cells while at the same time preserving and protecting the integrity of “self” …

Background Extracorporeal photopheresis (ECP) is commonly used to treat patients with
graft‐versus‐host disease (GVHD) and lung transplant rejection (LTR) in our institution. The …

Abstract The American Society for Apheresis (ASFA) Committee on Clinical Applications
systematically and critically reviews published information on the use of therapeutic …

Background: Extracorporeal photochemotherapy (EXP) is an immunomodulating therapy
that has been used in a limited number of patients with systemic sclerosis (SSC) with …

Abstract Purpose of Review Extracorporeal photochemotherapy (photopheresis, ECP) is a
cell-based immunomodulatory treatment that separates leukocytes from peripheral blood …