The term 'sclerosing diseases of the skin'comprises specific dermatological entities, which
have fibrotic changes of the skin in common. These diseases mostly manifest in different …

Background After the first investigational study on the use of extracorporeal photopheresis
for the treatment of cutaneous T‐cell lymphoma was published in 1983 with its subsequent …

Background Following the first investigational study on the use of extracorporeal
photopheresis for the treatment of cutaneous T‐cell lymphoma published in 1983, this …

The treatment of systemic sclerosis (scleroderma) is difficult and remains a great challenge
to the clinician. Because the cause is unknown, therapies are directed to improve peripheral …

Skin involvement in SSc is an important marker of disease activity, severity and prognosis,
making the assessment of skin a key issue in SSc clinical research. We reviewed the …

BACKGROUND: Systemic sclerosis is a multisystemic connective tissue disease with
marked involvement of the skin and joints for which few effective evidence based therapies …

Photopheresis or extracorporeal photochemotherapy (ECP) is a novel immunomodulatory
therapy which involves separation of the patient's leucocyte‐rich plasma, followed by ex vivo …

This literature review aimed to evaluate the effectiveness of rituximab (RTX) in patients with
systemic sclerosis (SSc). PubMed was searched for articles, published through 31 March …

Systemic sclerosis is a chronic progressive disease in which features of Raynaud's
phenomenon and vascular occlusion are followed by sclerotic and fibrotic changes in the …

Autologous hematopoietic stem cell transplantation (HSCT) utilizing a myeloablative
regimen containing total body irradiation has been performed in patients with systemic …