The global burden of chronic respiratory disease in adults
P Burney, D Jarvis… - The International Journal of …, 2015 - ingentaconnect.com
With an aging global population, chronic respiratory diseases are becoming a more
prominent cause of death and disability. Age-standardised death rates from chronic …
prominent cause of death and disability. Age-standardised death rates from chronic …
The promises and pitfalls of genoeconomics
This article reviews existing research at the intersection of genetics and economics, presents
some new findings that illustrate the state of genoeconomics research, and surveys the …
some new findings that illustrate the state of genoeconomics research, and surveys the …
[HTML][HTML] Novel insights into the genetics of smoking behaviour, lung function, and chronic obstructive pulmonary disease (UK BiLEVE): a genetic association study in …
Background Understanding the genetic basis of airflow obstruction and smoking behaviour
is key to determining the pathophysiology of chronic obstructive pulmonary disease (COPD) …
is key to determining the pathophysiology of chronic obstructive pulmonary disease (COPD) …
Sulforaphane: translational research from laboratory bench to clinic
Cruciferous vegetables are widely acknowledged to provide chemopreventive benefits in
humans, but they are not generally consumed at levels that effect significant change in …
humans, but they are not generally consumed at levels that effect significant change in …
Comparison and development of machine learning tools for the prediction of chronic obstructive pulmonary disease in the Chinese population
X Ma, Y Wu, L Zhang, W Yuan, L Yan, S Fan… - Journal of translational …, 2020 - Springer
Background Chronic obstructive pulmonary disease (COPD) is a major public health
problem and cause of mortality worldwide. However, COPD in the early stage is usually not …
problem and cause of mortality worldwide. However, COPD in the early stage is usually not …
Updates on the COPD gene list
Y Bossé - International journal of chronic obstructive pulmonary …, 2012 - Taylor & Francis
A genetic contribution to develop chronic obstructive pulmonary disease (COPD) is well
established. However, the specific genes responsible for enhanced risk or host differences …
established. However, the specific genes responsible for enhanced risk or host differences …
Role of transient receptor potential and pannexin channels in cigarette smoke-triggered ATP release in the lung
Background COPD is an inflammatory disease usually associated with cigarette smoking
(CS) with an increasing global prevalence and no effective medication. Extracellular ATP is …
(CS) with an increasing global prevalence and no effective medication. Extracellular ATP is …
Emerging genetics of COPD
A Berndt, AS Leme, SD Shapiro - EMBO molecular medicine, 2012 - embopress.org
Since the discovery of alpha‐1 antitrypsin in the early 1960s, several new genes have been
suggested to play a role in chronic obstructive pulmonary disease (COPD) pathogenesis …
suggested to play a role in chronic obstructive pulmonary disease (COPD) pathogenesis …
α-1-Antitrypsin deficiency: clinical variability, assessment, and treatment
RA Stockley, AM Turner - Trends in molecular medicine, 2014 - cell.com
The recognition of α-1-antitrypsin deficiency, its function, and its role in predisposition to the
development of severe emphysema was a watershed in our understanding of the …
development of severe emphysema was a watershed in our understanding of the …
Metalloproteases/anti-metalloproteases imbalance in chronic obstructive pulmonary disease: genetic factors and treatment implications
E Mocchegiani, R Giacconi… - Current opinion in …, 2011 - journals.lww.com
The disease is mainly caused by exposure to cigarette smoke or noxious gases and air
pollutants, but also genetic factors are involved. Among them, polymorphisms of MMPs …
pollutants, but also genetic factors are involved. Among them, polymorphisms of MMPs …