The long noncoding RNA nHOTAIRM1 is necessary for differentiation and activity of iPSC-derived spinal motor neurons
P Tollis, E Vitiello, F Migliaccio, E D'Ambra… - Cell Death & …, 2023 - nature.com
The mammalian nervous system is made up of an extraordinary array of diverse cells that
form intricate functional connections. The programs underlying cell lineage specification …
form intricate functional connections. The programs underlying cell lineage specification …
Mitochondrial glutamine transporter SLC1A5_var, a potential target to suppress astrocyte reactivity in Parkinson's Disease
Y Liu, L Cao, Y Song, Z Kang, T Liu, J Ding, G Hu… - Cell Death & …, 2022 - nature.com
Abstract SLC1A5 variant (SLC1A5_var) is identified as a mitochondrial glutamine
transporter in cancer cells recently. However, the role of SLC1A5_var in Parkinson's disease …
transporter in cancer cells recently. However, the role of SLC1A5_var in Parkinson's disease …
KATP channels as ROS-dependent modulator of neurotransmitter release at the neuromuscular junctions
AN Tsentsevitsky, CR Gafurova, AM Petrov - Life Sciences, 2022 - Elsevier
Aims Neurotransmitter release requires high energy demands, making the nerve terminals
metabolically fragile and susceptible to oxidative stress. ATP-sensitive potassium (K ATP) …
metabolically fragile and susceptible to oxidative stress. ATP-sensitive potassium (K ATP) …
GPBAR1 preserves neurite and synapse of dopaminergic neurons via RAD21-OPCML signaling: Role in preventing Parkinson's disease in mouse model and human …
Y Zhang, X Sun, Y Zhang, Z Kang, L Cai, J Ding… - Pharmacological …, 2022 - Elsevier
Parkinson's disease (PD) exhibits systemic impacts on the metabolism, while metabolic
alteration contributes to the risk and progression of PD. Bile acids (BA) metabolism …
alteration contributes to the risk and progression of PD. Bile acids (BA) metabolism …
Alzheimer's Disease-Associated SNP rs708727 in SLC41A1 May Increase Risk for Parkinson's Disease: Report from Enlarged Slovak Study
M Cibulka, M Brodnanova, M Grendar… - International journal of …, 2022 - mdpi.com
SLC41A1 (A1) SNPs rs11240569 and rs823156 are associated with altered risk for
Parkinson's disease (PD), predominantly in Asian populations, and rs708727 has been …
Parkinson's disease (PD), predominantly in Asian populations, and rs708727 has been …
Decoding the role of the lncRNA HOTAIRM1 in human motor neurons
P Tollis - 2023 - iris.uniroma1.it
The mammalian genome produces thousands of long non-coding RNAs (lncRNAs), which
have been demonstrated to be fundamental in the control of many biological processes …
have been demonstrated to be fundamental in the control of many biological processes …