Carbapenem-resistant Klebsiella pneumoniae: the role of plasmids in emergence, dissemination and evolution of a major clinical challenge

V Di Pilato, S Pollini, V Miriagou… - Expert Review of Anti …, 2024 - Taylor & Francis
Introduction Klebsiella pneumoniae is a major agent of healthcare-associated infections and
a cause of some community-acquired infections, including severe bacteremic infections …

[HTML][HTML] Presence of hypervirulence-associated determinants in Klebsiella pneumoniae from hospitalised patients in Germany

A Wahl, MA Fischer, K Klaper, A Müller… - International Journal of …, 2024 - Elsevier
Background Klebsiella (K.) pneumoniae is a ubiquitous Gram-negative bacterium and a
common coloniser of animals and humans. Today, K. pneumoniae is one of the most …

Genomic insights unveil the plasmid transfer mechanism and epidemiology of hypervirulent Klebsiella pneumoniae in Vietnam

Q Nguyen, YTP Nguyen, TT Ha, DTN Tran… - Nature …, 2024 - nature.com
Hypervirulent Klebsiella pneumoniae (hvKp) is a significant cause of severe invasive
infections in Vietnam, yet data on its epidemiology, population structure and dynamics are …

Comparative analysis of multidrug-resistant Klebsiella pneumoniae strains of food and human origin reveals overlapping populations

S Silva-Bea, M Romero, A Parga, J Fernández… - International Journal of …, 2024 - Elsevier
Given the increasing incidence of multidrug-resistant (MDR) Klebsiella pneumoniae
infections, it is of great interest to investigate the risk of transmission associated with the …

Klebsiella pneumoniae sequence type 147: a high-risk clone increasingly associated with plasmids carrying both resistance and virulence elements

JF Turton, C Perry, K McGowan… - Journal of Medical …, 2024 - microbiologyresearch.org
Introduction. The first hybrid resistance/virulence plasmid, combining elements from
virulence plasmids described in hypervirulent types of Klebsiella pneumoniae with those …

Should multidrug resistant Klebsiella pneumoniae strains displaying hypervirulent traits be reclassified as either ultravirulent or supervirulent?

B Douradinha - Microbiological Research, 2023 - Elsevier
Historically, Klebsiella pneumoniae isolates were described either as hypervirulent or
classical. While hypervirulent strains display a precise phenotype (thicker capsule …

Screening of Klebsiella pneumoniae Isolates for Carbapenemase and Hypervirulence-Associated Genes by Combining the Eazyplex® Superbug CRE and hvKp …

J Rödel, Y Pfeifer, MA Fischer, B Edel, S Stoll, W Pfister… - Antibiotics, 2023 - mdpi.com
The acquisition of hypervirulence-associated genes by carbapenemase-producing
Klebsiella pneumoniae is being increasingly observed, and easy-to-use diagnostic tests are …

RETRACTED: Drug Resistance and Molecular Characteristics of Carbapenem-Resistant OXA-48-Producing Klebsiella pneumoniae Strains in Hainan, China

M Ye, L Liu, B Liu, X Zhou, Q Li - Microorganisms, 2023 - mdpi.com
Background: The emergence and global spread of carbapenem-resistant hypervirulent
Klebsiella pneumoniae (CR-hvKP) are of great concern to health services worldwide. These …

Screening of Klebsiella pneumoniae subsp. pneumoniae Strains with Multi-Drug Resistance and Virulence Profiles Isolated from an Italian Hospital between 2020 …

V Dimartino, C Venditti, F Messina, S D'Arezzo… - Antibiotics, 2024 - mdpi.com
Klebsiella pneumoniae strains that are resistant to multiple drugs (KPMDRs), which are
often acquired in hospital settings and lead to healthcare-associated infections, pose a …

Extensive Expression of the Virulome Related to Antibiotic Genotyping in Nosocomial Strains of Klebsiella pneumoniae

GL Paniagua-Contreras, A Bautista-Cerón… - International Journal of …, 2023 - mdpi.com
The emergence of hyper-virulent and multidrug-resistant (MDR) strains of Klebsiella
pneumoniae isolated from patients with hospital-and community-acquired infections is a …