Natural killer cells (NK cells) are the first line of the innate immune defense system, primarily
located in peripheral circulation and lymphoid tissues. They kill virally infected and …

Abstract mRNA formulated with lipid nanoparticles is a transformative technology that has
enabled the rapid development and administration of billions of coronavirus disease 2019 …

Central serous chorioretinopathy (CSC) is a common form of vision loss, typically seen in
working-age men. The pathophysiology behind CSC still eludes us, however significant …

Regenerative medicine aims to replace the lost or damaged cells in the human body
through a new source of healthy transplanted cells or by endogenous repair. Although …

Neurodegenerative diseases, such as Alzheimer's disease (AD), Parkinson's disease (PD),
Huntington's disease (HD) and amyotrophic lateral sclerosis (ALS), affect millions of people …

The liver plays critical roles in both homeostasis and pathology. It is the major site of drug
metabolism in the body and, as such, a common target for drug-induced toxicity and is …

The applications of modern artificial intelligence (AI) algorithms within the field of aging
research offer tremendous opportunities. Aging is an almost universal unifying feature …

Wound healing is the physiologic response to a disruption in normal skin architecture and
requires both spatial and temporal coordination of multiple cell types and cytokines. This …

Although skeletal muscle repairs itself following small injuries, genetic diseases or severe
damages may hamper its ability to do so. Induced pluripotent stem cells (iPSCs) can …

Animals often fail to faithfully mimic human diseases and drug toxicities, and most in vitro
models are not complex enough to recapitulate human body function and pathophysiology …