The treatment options for systemic light chain amyloidosis (AL) are currently widening in an
unprecedented way, brought about by an expanding arsenal of anti-myeloma therapy as …

Background Left ventricular pressure-strain–derived myocardial work index (LVMWI) is a
novel, noninvasive method for left ventricular (LV) function evaluation in relation to LV …

About one-half of the patients with congestive heart failure have preserved left ventricular
ejection fraction (HFpEF). Although the etiology of HFpEF is most commonly related to long …

Primary light chain amyloidosis is the most common form of systemic amyloidosis and is
caused by misfolded light chains that cause proteotoxicity and rapid decline of vital organ …

Systemic amyloidosis is generally considered to be rare, but the heart is frequently involved
and is a major determinant of prognosis. New diagnostic imaging methods have recently …

Background Cardiac amyloidosis (CA) is associated with a poor prognosis with the
proposed mechanism of sudden cardiac death in the majority of patients being pulseless …

Objectives: This study evaluated whether 2-dimensional speckle-tracking echocardiography
(2D-STE) has incremental value for prognosis over traditional clinical, echocardiographic …

Objectives Quantification of myocardial deformation by feature tracking is of growing interest
in cardiovascular magnetic resonance. It allows the assessment of regional myocardial …

Cardiac amyloidosis in the United States is most often due to myocardial infiltration by
immunoglobulin protein, such as in AL amyloidosis, or by the protein transthyretin, such as …

Amyloidosis is a disorder of protein misfolding and metabolism in which insoluble fibrils are
deposited in various tissues, causing organ dysfunction and eventually death. Out of the 60 …