[PDF][PDF] Smchd1-dependent and-independent pathways determine developmental dynamics of CpG island methylation on the inactive X chromosome

AV Gendrel, A Apedaile, H Coker, A Termanis… - Developmental cell, 2012 - cell.com
X chromosome inactivation involves multiple levels of chromatin modification, established
progressively and in a stepwise manner during early development. The chromosomal …

DNA methylation in mouse gametogenesis

R Marchal, A Chicheportiche, B Dutrillaux… - … and genome research, 2004 - karger.com
DNA methylation is involved in many biological processes and is particularly important for
both development and germ cell differentiation. Several waves of demethylation and de …

Global changes in epigenomes during mouse spermatogenesis: possible relation to germ cell apoptosis

T Koji, Y Shibata - Histochemistry and Cell Biology, 2020 - Springer
Mammalian spermatogenesis is characterized by disproportionate germ cell apoptosis. The
high frequency of apoptosis is considered a safety mechanism that serves to avoid …

Late-replicating heterochromatin is characterized by decreased cytosine methylation in the human genome

M Suzuki, M Oda, MP Ramos, M Pascual… - Genome …, 2011 - genome.cshlp.org
Heterochromatin is believed to be associated with increased levels of cytosine methylation.
With the recent availability of genome-wide, high-resolution molecular data reflecting …

5-aza-2′-deoxycytidine impairs mouse spermatogenesis at multiple stages through different usage of DNA methyltransferases

N Song, D Endo, B Song, Y Shibata, T Koji - Toxicology, 2016 - Elsevier
Mammalian spermatogenesis is a progressive process comprising spermatogonial
proliferation, spermatocytic meiosis, and later spermiogenesis, which is considered to be …

Short stature and primary ovarian insufficiency possibly due to chromosomal position effect in a balanced X; 1 translocation

R Genesio, A Mormile, MR Licenziati, D De Brasi… - Molecular …, 2015 - Springer
Background Primary ovarian insufficiency (POI) is defined as a primary ovarian defect
characterized by absent menarche (primary amenorrhea), a decrease in the initial primordial …

[HTML][HTML] Age-related changes in the localization of DNA methyltransferases during meiotic maturation in mouse oocytes

L Zhang, DY Lu, WY Ma, Y Li - Fertility and sterility, 2011 - Elsevier
The effects of maternal aging on the localization of DNA methyltransferases were evaluated
during mouse oocyte maturation using fluorescence staining. And we conclude that …

神经母细胞瘤中的基因甲基化

吴迪, 张可仞 - 中华小儿外科杂志, 2011 - cqvip.com
神经母细胞瘤(neuroblastoma, NB) 是幼儿期常见的恶性实体肿瘤之一, 占儿童恶性肿瘤的8%~
10%, 年发病率为(0.3~ 5.5)/10 万, 仅低于白血病和中枢神经系统肿瘤, 80% 病例发生于5 …

DNA methylation: an epigenetic marker of breast cancer influenced by nutrients acting as an environmental factor

TN Hasan, G Shafi, BL Grace… - … Mol. Markers Gynecol …, 2015 - api.taylorfrancis.com
ABSTRACT DNA methylation is an important regulator of gene expression and plays an
essential role in maintaining cellular function. Its role in carcinogenesis has been a topic of …

DNA Methylation: An Epigenetic Marker of Breast Cancer Influenced by Nutrients Acting as an Environmental Factor

A Munshi - Noninvasive Molecular Markers in Gynecologic …, 2015 - taylorfrancis.com
ABSTRACT DNA methylation is an important regulator of gene expression and plays an
essential role in maintaining cellular function. Its role in carcinogenesis has been a topic of …