Anticancer potential of alkaloids: a key emphasis to colchicine, vinblastine, vincristine, vindesine, vinorelbine and vincamine

P Dhyani, C Quispe, E Sharma, A Bahukhandi… - Cancer cell …, 2022 - Springer
Cancer, one of the leading illnesses, accounts for about 10 million deaths worldwide. The
treatment of cancer includes surgery, chemotherapy, radiation therapy, and drug therapy …

Potential mechanisms of quercetin in cancer prevention: focus on cellular and molecular targets

P Asgharian, AP Tazekand, K Hosseini… - Cancer cell …, 2022 - Springer
Over the past few years, the cancer-related disease has had a high mortality rate and
incidence worldwide, despite clinical advances in cancer treatment. The drugs used for …

Diosgenin: an updated pharmacological review and therapeutic perspectives

P Semwal, S Painuli, T Abu-Izneid… - Oxidative medicine …, 2022 - Wiley Online Library
Plants including Rhizoma polgonati, Smilax china, and Trigonella foenum-graecum contain
a lot of diosgenin, a steroidal sapogenin. This bioactive phytochemical has shown high …

Recent advances and limitations of mTOR inhibitors in the treatment of cancer

ES Ali, K Mitra, S Akter, S Ramproshad, B Mondal… - Cancer cell …, 2022 - Springer
Abstract The PI3K-Akt-mechanistic (formerly mammalian) target of the rapamycin (mTOR)
signaling pathway is important in a variety of biological activities, including cellular …

The Pharmacological Activities of Crocus sativus L.: A Review Based on the Mechanisms and Therapeutic Opportunities of its Phytoconstituents

M Butnariu, C Quispe, J Herrera-Bravo… - Oxidative medicine …, 2022 - Wiley Online Library
Crocus species are mainly distributed in North Africa, Southern and Central Europe, and
Western Asia, used in gardens and parks as ornamental plants, while Crocus sativus …

[HTML][HTML] Rosmarinic acid and its derivatives: Current insights on anticancer potential and other biomedical applications

S Ijaz, J Iqbal, BA Abbasi, Z Ullah, T Yaseen… - Biomedicine & …, 2023 - Elsevier
Cancer is still the leading cause of death worldwide, burdening the global medical system.
Rosmarinic acid (RA) is among the first secondary metabolites discovered and it is a …

Recent updates on anticancer mechanisms of polyphenols

E Sharma, DC Attri, P Sati, P Dhyani… - Frontiers in Cell and …, 2022 - frontiersin.org
In today's scenario, when cancer cases are increasing rapidly, anticancer herbal
compounds become imperative. Studies on the molecular mechanisms of action of …

Anticancer Potential and Other Pharmacological Properties of Prunus armeniaca L.: An Updated Overview

D Kitic, B Miladinovic, M Randjelovic, A Szopa… - Plants, 2022 - mdpi.com
Prunus armeniaca L.(Rosaceae)-syn. Amygdalus armeniaca (L.) Dumort., Armeniaca
armeniaca (L.) Huth, Armeniaca vulgaris Lam is commonly known as the apricot tree. The …

Biosensing chips for cancer diagnosis and treatment: a new wave towards clinical innovation

MJ Iqbal, Z Javed, J Herrera-Bravo, H Sadia… - Cancer Cell …, 2022 - Springer
Recent technological advances in nanoscience and material designing have led to the
development of point-of-care devices for biomolecule sensing and cancer diagnosis. In situ …

[HTML][HTML] The exposome and liver disease-how environmental factors affect liver health

R Barouki, M Samson, EB Blanc, M Colombo… - Journal of …, 2023 - Elsevier
Since the initial development of the exposome concept, much effort has been devoted to the
characterisation of the exposome through analytical, epidemiological, and toxicological …