Environmental enrichment decreases cell surface expression of the dopamine transporter in rat medial prefrontal cortex

J Zhu, S Apparsundaram, MT Bardo… - Journal of …, 2005 - Wiley Online Library
Rats raised in an enriched environmental condition (EC) exhibit a decreased (35%) maximal
velocity (Vmax) of [3H] dopamine (DA) uptake in medial prefrontal cortex (mPFC) compared …

Conditioned place preference and locomotor activation produced by injection of psychostimulants into ventral pallidum

W Gong, D Neill, JB Justice Jr - Brain research, 1996 - Elsevier
The ventral pallidum (VP) is often viewed as an output structure of the nucleus accumbens
septi (NAS). However, VP, like NAS, receives a dopaminergic input from the ventral …

Chronic cocaine enhances serotonin autoregulation and serotonin uptake binding

KA Cunningham, JM Paris, NE Goeders - Synapse, 1992 - Wiley Online Library
Repeated cocaine intoxication can result in the development of behavioral sensitization in
animals and psychosis in humans, phenomena that have been associated with alterations in …

The whisker nuisance task identifies a late-onset, persistent sensory sensitivity in diffuse brain-injured rats

KCS McNamara, AM Lisembee, J Lifshitz - Journal of neurotrauma, 2010 - liebertpub.com
Post-traumatic morbidity reduces the quality of life for traumatic brain injury (TBI) survivors by
altering neuropsychological function. After midline fluid percussion injury (FPI), diffuse …

The transition from controlled to compulsive drug use is associated with a loss of sensitization

O Ben-Shahar, SH Ahmed, GF Koob, A Ettenberg - Brain research, 2004 - Elsevier
Rats provided limited daily access to cocaine (1 h) maintain stable levels of drug self-
administration over time while those switched to longer access (6 h or more) exhibit …

Altered Fos expression in neural pathways underlying cue‐elicited drug seeking in the rat

CA Miller, JF Marshall - European Journal of Neuroscience, 2005 - Wiley Online Library
Cocaine treatment paired with environmental cues establishes a conditioned place
preference for that environment. Following expression of this preference, rats show elevated …

Altered prelimbic cortex output during cue-elicited drug seeking

CA Miller, JF Marshall - Journal of Neuroscience, 2004 - Soc Neuroscience
Cocaine treatment paired with environmental cues establishes a conditioned place
preference (CPP) for that environment. After expression of this preference, rats show …

Role of the prelimbic subregion of the medial prefrontal cortex in acquisition, extinction, and reinstatement of cocaine-conditioned place preference

AR Zavala, SM Weber, HJ Rice, AT Alleweireldt… - Brain research, 2003 - Elsevier
Previous research suggests that the prelimbic subregion of the medial prefrontal cortex
(mPFC) is necessary for acquisition of cocaine-conditioned place preference (CPP) …

6-Hydroxydopamine lesion of ventral pallidum blocks acquisition of place preference conditioning to cocaine

W Gong, D Neill, JB Justice Jr - Brain research, 1997 - Elsevier
In parallel with nucleus accumbens (NAS), ventral pallidum (VP) also receives a
dopaminergic projection from the ventral tegmental area (VTA). The present study examined …

Glutamatergic neurons in the medial prefrontal cortex mediate the formation and retrieval of cocaine‐associated memories in mice

T Zhang, J Yanagida, H Kamii, S Wada… - Addiction …, 2020 - Wiley Online Library
In drug addiction, environmental stimuli previously associated with cocaine use readily elicit
cocaine‐associated memories, which persist long after abstinence and trigger cocaine …