As disease-specific interventions for dementia are being developed, the ability to identify the
underlying pathology and dementia subtypes is increasingly important. Vascular cognitive …

Cognitive dysfunctions such as mild cognitive impairment (MCI), Alzheimer's disease (AD),
and other forms of dementia are recognized as common comorbidities of type 2 diabetes …

Alzheimer's disease (AD) accounts for two-thirds of all dementia cases, affecting 50 million
people worldwide. Only four of the more than 100 AD drugs developed thus far have …

Reactive oxygen species (ROS) have emerged as essential signaling molecules regulating
cell survival, death, inflammation, differentiation, growth, and immune response …

Brain-derived neurotrophic factor (BDNF) is the most abundant neurotrophin in the adult
brain and functions as both a primary neurotrophic signal and a neuromodulator. It serves …

Background Brain-derived neurotrophic factor (BDNF) is a neurotrophic factor expressed in
several tissues, including the brain, gut, and pancreas. Activation of the BDNF/TrkB/CREB …

This review reflects upon our own as well as other investigators' studies on the role of
receptor for advanced glycation end-products (RAGE), bringing up the latest information on …

Diabetic cognitive impairment (DCI) is a serious neurodegenerative disorder caused by
diabetes, with chronic inflammation being a crucial factor in its pathogenesis. Pterostilbene …

Depression is one of the most common mental diseases, with increasing numbers of
patients globally each year. In addition, approximately 30% of patients with depression are …

Cognitive impairment is the main central nervous system complication of diabetes, affecting
the quality of life of patients. Herba Cistanche is a homologous plant widely used as a health …