Pathogenesis and virulence of Candida albicans
JP Lopes, MS Lionakis - Virulence, 2022 - Taylor & Francis
Candida albicans is a commensal yeast fungus of the human oral, gastrointestinal, and
genital mucosal surfaces, and skin. Antibiotic-induced dysbiosis, iatrogenic …
genital mucosal surfaces, and skin. Antibiotic-induced dysbiosis, iatrogenic …
The impact of the Fungus-Host-Microbiota interplay upon Candida albicans infections: current knowledge and new perspectives
C d'Enfert, AK Kaune, LR Alaban… - FEMS microbiology …, 2021 - academic.oup.com
Candida albicans is a major fungal pathogen of humans. It exists as a commensal in the oral
cavity, gut or genital tract of most individuals, constrained by the local microbiota, epithelial …
cavity, gut or genital tract of most individuals, constrained by the local microbiota, epithelial …
Immunity to fungi in the lung
LJ Heung, DL Wiesner, K Wang, A Rivera… - Seminars in immunology, 2023 - Elsevier
The respiratory tree maintains sterilizing immunity against human fungal pathogens.
Humans inhale ubiquitous filamentous molds and geographically restricted dimorphic fungal …
Humans inhale ubiquitous filamentous molds and geographically restricted dimorphic fungal …
[HTML][HTML] Immunosurveillance of Candida albicans commensalism by the adaptive immune system
M Swidergall, S LeibundGut-Landmann - Mucosal immunology, 2022 - Elsevier
The fungal microbiota (mycobiota) is an integral part of the microbial community colonizing
the body surfaces and is involved in many key aspects of human physiology, while an …
the body surfaces and is involved in many key aspects of human physiology, while an …
[HTML][HTML] New insights in Candida albicans innate immunity at the mucosa: toxins, epithelium, metabolism, and beyond
A Pellon, SD Sadeghi Nasab… - Frontiers in cellular and …, 2020 - frontiersin.org
The mucosal surfaces of the human body are challenged by millions of microbes on a daily
basis. Co-evolution with these microbes has led to the development of plastic mechanisms …
basis. Co-evolution with these microbes has led to the development of plastic mechanisms …
PAMPs of the fungal cell wall and mammalian PRRs
Fungi are opportunistic pathogens that infect immunocompromised patients and are
responsible for an estimated 1.5 million deaths every year. The antifungal innate immune …
responsible for an estimated 1.5 million deaths every year. The antifungal innate immune …
[HTML][HTML] The interactions between Candida albicans and mucosal immunity
Mucosa protects the body against external pathogen invasion. However, pathogen colonies
on the mucosa can invade the mucosa when the immunosurveillance is compromised …
on the mucosa can invade the mucosa when the immunosurveillance is compromised …
[HTML][HTML] Mucosal IgA prevents commensal Candida albicans dysbiosis in the oral cavity
N Millet, NV Solis, M Swidergall - Frontiers in Immunology, 2020 - frontiersin.org
The fungus Candida albicans colonizes the oral mucosal surface of 30–70% of healthy
individuals. Due to local or systemic immunosuppression, this commensal fungus is able to …
individuals. Due to local or systemic immunosuppression, this commensal fungus is able to …
[HTML][HTML] Activation of EphA2-EGFR signaling in oral epithelial cells by Candida albicans virulence factors
M Swidergall, NV Solis, N Millet, MY Huang… - PLoS …, 2021 - journals.plos.org
During oropharyngeal candidiasis (OPC), Candida albicans invades and damages oral
epithelial cells, which respond by producing proinflammatory mediators that recruit …
epithelial cells, which respond by producing proinflammatory mediators that recruit …