[HTML][HTML] Kinase inhibitors as potential therapeutic agents in the treatment of COVID-19

RR Naik, AK Shakya, SM Aladwan… - Frontiers in …, 2022 - frontiersin.org
Corona virus is quickly spreading around the world. The goal of viral management is to
disrupt the virus's life cycle, minimize lung damage, and alleviate severe symptoms …

[HTML][HTML] Molecular Mechanisms Responsible for the Therapeutic Potential of Mesenchymal Stem Cell-Derived Exosomes in the Treatment of Lung Fibrosis

CR Harrell, V Djonov, A Volarevic… - International journal of …, 2024 - mdpi.com
Mesenchymal stem cell-derived exosomes (MSC-Exos) are nano-sized extracellular
vesicles which contain various MSC-sourced anti-fibrotic, immunoregulatory and angio …

Investigating rutin as a potential transforming growth factor‐β type I receptor antagonist for the inhibition of bleomycin‐induced lung fibrosis

WAHM Karunarathne, KT Lee, YH Choi, CH Kang… - …, 2024 - Wiley Online Library
Idiopathic pulmonary fibrosis (IPF) is a chronic lung condition characterized by the abnormal
regulation of extracellular matrix (ECM) and epithelial‐mesenchymal transition (EMT). In this …

[HTML][HTML] Current and prospective applications of exosomal microRNAs in pulmonary fibrosis

T Yang, J Wang, J Zhao, Y Liu - … Journal of Molecular …, 2022 - spandidos-publications.com
Pulmonary fibrosis (PF) is a chronic, progressive, irreversible and life‑threatening lung
disease. However, the pathogenesis and molecular mechanisms of this condition remain …

[HTML][HTML] GRADE-ADOLOPMENT of clinical practice guidelines and creation of clinical pathways for the primary care management of chronic respiratory conditions in …

RS Martins, H Hussain, M Chaudry, NA Rizvi… - BMC Pulmonary …, 2023 - Springer
Abstract Introduction In Pakistan, chronic respiratory conditions contribute a large burden of
morbidity and mortality. A major reason for this is the lack of availability of local evidence …

[HTML][HTML] An overview of CCN4 (WISP1) role in human diseases

K Singh, SS Oladipupo - Journal of Translational Medicine, 2024 - Springer
CCN4 (cellular communication network factor 4), a highly conserved, secreted cysteine-rich
matricellular protein is emerging as a key player in the development and progression of …

Airway basal cell‑derived exosomes suppress epithelial‑mesenchymal transition of lung cells by inhibiting the expression of ANO1

X Gu, Z Liu, S Shan, T Ren… - Experimental and …, 2024 - spandidos-publications.com
Disruption of the epithelial‑mesenchymal transition (EMT) of activated lung cells is an
important strategy to inhibit the progression of idiopathic pulmonary fibrosis (IPF). The …

Role and targeting of the AGC kinase family in pulmonary fibrosis

C Mei, T Chen, X Huang… - Experimental and …, 2024 - spandidos-publications.com
Pulmonary fibrosis (PF) is a progressive and irreversible pulmonary disease with a high
mortality rate and limited treatment options. The cAMP‑dependent protein kinase A, cGMP …

Epigenetics of Idiopathic Pulmonary Fibrosis

SK Singh, SS Tanwar, D Patel, P Yadav… - Targeting Epigenetics in …, 2023 - Springer
Idiopathic pulmonary fibrosis (IPF) is a fatal variation of the interstitial pulmonary illness
characterised by extracellular matrix deposition that leads to secretion of inflammatory …

miR-200c prevents and reverts Lung fibrosis by down regulating Flt1 and promoting lung regeneration

MC Volpe - 2022 - arts.units.it
Idiopathic pulmonary fibrosis (IPF) is a devastating progressive fibrotic disease affecting the
lungs and causing chronic respiratory failure. In IPF, adult alveolar type II stem cells (ATII) …