[HTML][HTML] SARS-CoV-2 vaccines based on the spike glycoprotein and implications of new viral variants
D Martínez-Flores, J Zepeda-Cervantes… - Frontiers in …, 2021 - frontiersin.org
Coronavirus 19 Disease (COVID-19) originating in the province of Wuhan, China in 2019, is
caused by the severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2), whose …
caused by the severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2), whose …
[HTML][HTML] Virus-like particles: Revolutionary platforms for developing vaccines against emerging infectious diseases
Virus-like particles (VLPs) are nanostructures that possess diverse applications in
therapeutics, immunization, and diagnostics. With the recent advancements in biomedical …
therapeutics, immunization, and diagnostics. With the recent advancements in biomedical …
The multifaceted biology of PCSK9
NG Seidah, A Prat - Endocrine reviews, 2022 - academic.oup.com
This article reviews the discovery of PCSK9, its structure–function characteristics, and its
presently known and proposed novel biological functions. The major critical function of …
presently known and proposed novel biological functions. The major critical function of …
Adjuvant physiochemistry and advanced nanotechnology for vaccine development
Vaccines comprising innovative adjuvants are rapidly reaching advanced translational
stages, such as the authorized nanotechnology adjuvants in mRNA vaccines against COVID …
stages, such as the authorized nanotechnology adjuvants in mRNA vaccines against COVID …
SARS-CoV-2 RBD-tetanus toxoid conjugate vaccine induces a strong neutralizing immunity in preclinical studies
Y Valdes-Balbin, D Santana-Mederos… - ACS Chemical …, 2021 - ACS Publications
Controlling the global COVID-19 pandemic depends, among other measures, on developing
preventive vaccines at an unprecedented pace. Vaccines approved for use and those in …
preventive vaccines at an unprecedented pace. Vaccines approved for use and those in …
Human ZBP1 induces cell death‐independent inflammatory signaling via RIPK3 and RIPK1
ZBP1 is an interferon‐induced cytosolic nucleic acid sensor that facilitates antiviral
responses via RIPK3. Although ZBP1‐mediated programmed cell death is widely described …
responses via RIPK3. Although ZBP1‐mediated programmed cell death is widely described …
Molecular aspects concerning the use of the SARS-CoV-2 receptor binding domain as a target for preventive vaccines
Y Valdes-Balbin, D Santana-Mederos… - ACS central …, 2021 - ACS Publications
The development of recombinant COVID-19 vaccines has resulted from scientific progress
made at an unprecedented speed during 2020. The recombinant spike glycoprotein …
made at an unprecedented speed during 2020. The recombinant spike glycoprotein …
[HTML][HTML] Hemorrhagic fever with renal syndrome in Asia: history, pathogenesis, diagnosis, treatment, and prevention
A Sehgal, S Mehta, K Sahay, E Martynova, A Rizvanov… - Viruses, 2023 - mdpi.com
Hemorrhagic Fever with Renal Syndrome (HFRS) is the most frequently diagnosed zoonosis
in Asia. This zoonotic infection is the result of exposure to the virus-contaminated aerosols …
in Asia. This zoonotic infection is the result of exposure to the virus-contaminated aerosols …
[HTML][HTML] Biological nanoparticles in vaccine development
SM Curley, D Putnam - Frontiers in Bioengineering and …, 2022 - frontiersin.org
Vaccines represent one of the most successful public health initiatives worldwide. However,
despite the vast number of highly effective vaccines, some infectious diseases still do not …
despite the vast number of highly effective vaccines, some infectious diseases still do not …
[HTML][HTML] SARS-CoV-2 structural features may explain limited neutralizing-antibody responses
MF Bachmann, MO Mohsen, L Zha, M Vogel… - npj Vaccines, 2021 - nature.com
Neutralizing antibody responses of SARS-CoV-2-infected patients may be low and of short
duration. We propose here that coronaviruses employ a structural strategy to avoid strong …
duration. We propose here that coronaviruses employ a structural strategy to avoid strong …