Riboflavin derivatives are essential cofactors for a myriad of flavoproteins. In bacteria, flavins
importance extends beyond their role as intracellular protein cofactors, as secreted flavins …

Brown-Vialetto-Van Laere syndrome is a rare neurological disorder with a variable age at
onset and clinical course. The key features are progressive ponto-bulbar palsy and bilateral …

Riboflavin transporter deficiency (RTD) is a rare neurological condition that encompasses
the Brown‐Vialetto‐Van Laere and Fazio‐Londe syndromes since the discovery of …

Riboflavin, a water-soluble vitamin also known as vitamin B2, is essential for normal cellular
functions. Riboflavin transporters play important roles in its homeostasis. Recently, three …

We isolated cDNA coding a new human riboflavin transporter (hRFT) 3, which exhibits 86.7
and 44.1% amino acid identity with hRFT1 and hRFT2, respectively. It was predicted to have …

Riboflavin, the precursor for the cofactors flavin mononucleotide (FMN) and flavin adenine
dinucleotide, is an essential metabolite in all organisms. While the functions for de novo …

Introduction Riboflavin (vitamin B2) is absorbed in the small intestine by the human
riboflavin transporters RFVT1 and RFVT3. A third riboflavin transporter (RFVT2) is …

Abstract The Major Facilitator Superfamily (MFS) is currently the largest characterized
superfamily of transmembrane secondary transport proteins. Its diverse members are found …

Active targeting can improve the retention of drugs and drug delivery systems in tumors,
thereby enhancing their therapeutic efficacy. In this context, vitamin receptors that are …

Abstract The Concise Guide to PHARMACOLOGY 2013/14 provides concise overviews of
the key properties of over 2000 human drug targets with their pharmacology, plus links to an …