Timing of lifespan influences on brain and cognition

KB Walhovd, M Lövden, AM Fjell - Trends in cognitive sciences, 2023 - cell.com
Modifiable risk and protective factors for boosting brain and cognitive development and
preventing neurodegeneration and cognitive decline are embraced in neuroimaging …

The influence of virus infection on microglia and accelerated brain aging

L Filgueira, A Larionov, N Lannes - Cells, 2021 - mdpi.com
Microglia are the resident immune cells of the central nervous system contributing
substantially to health and disease. There is increasing evidence that inflammatory microglia …

A strong dependency between changes in fluid and crystallized abilities in human cognitive aging

EM Tucker-Drob, J De la Fuente, Y Köhncke… - Science …, 2022 - science.org
Theories of adult cognitive development classically distinguish between fluid abilities, which
require effortful processing at the time of assessment, and crystallized abilities, which …

Individual differences in brain aging: heterogeneity in cortico-hippocampal but not caudate atrophy rates

L Nyberg, M Andersson, A Lundquist… - Cerebral …, 2023 - academic.oup.com
It is well documented that some brain regions, such as association cortices, caudate, and
hippocampus, are particularly prone to age-related atrophy, but it has been hypothesized …

A neuroimaging signature of cognitive aging from whole‐brain functional connectivity

R Jiang, D Scheinost, N Zuo, J Wu, S Qi… - Advanced …, 2022 - Wiley Online Library
Cognitive decline is amongst one of the most commonly reported complaints during normal
aging. Despite evidence that age and cognition are linked with similar neural correlates, no …

Predictors of longitudinal cognitive ageing from age 70 to 82 including APOE e4 status, early-life and lifestyle factors: the Lothian Birth Cohort 1936

J Corley, F Conte, SE Harris, AM Taylor… - Molecular …, 2023 - nature.com
Discovering why some people's cognitive abilities decline more than others is a key
challenge for cognitive ageing research. The most effective strategy may be to address …

Cerebral small vessel disease burden and longitudinal cognitive decline from age 73 to 82: the Lothian Birth Cohort 1936

OKL Hamilton, SR Cox, JA Okely, F Conte… - Translational …, 2021 - nature.com
Slowed processing speed is considered a hallmark feature of cognitive decline in cerebral
small vessel disease (SVD); however, it is unclear whether SVD's association with slowed …

Longitudinal changes in gray matter correspond to changes in cognition across the lifespan: implications for theories of cognition

ET Smith, JP Hennessee, GS Wig, S Frank… - Neurobiology of …, 2023 - Elsevier
The present study examines the association between gray matter volume and cognition.
Studies that have examined this issue have focused primarily on older adults, whereas the …

Sleep quality, perivascular spaces and brain health markers in ageing-A longitudinal study in the Lothian Birth Cohort 1936

BS Aribisala, MCV Hernández, JA Okely, SR Cox… - Sleep medicine, 2023 - Elsevier
Background Sleep is thought to play a major role in brain health and general wellbeing.
However, few longitudinal studies have explored the relationship between sleep habits and …

Neurocognitive Aging

SR Cox - Annual Review of Developmental Psychology, 2024 - annualreviews.org
On average, most aspects of adult human brains and cognitive functions experience decline
with age, yet individuals also differ greatly in how much decline they experience. This review …