Intrahepatic cholangiocarcinomas (ICC) are neoplasms that originate from cholangiocytes
and can occur at any level of the biliary tree. Surgical resection is the current therapy of …

The worldwide incidence of cholangiocarcinoma (CC) is steadily rising, with the incidence in
United Kingdom (UK) incidence now exceeding 1000 cases per year. It is an aggressive …

Purpose Biomarkers for patients with resected cholangiocarcinoma (CC) can improve
staging and may ultimately result in personalized medicine. Studies evaluating these …

Results: A total of 11 publications met the criteria and included 943 cases. Analysis of these
data showed that COX-2 expression was not significantly correlated with capsular formation …

Matrix metalloproteinase-9 (MMP-9) is an important enzyme in tumor invasion and
metastasis in malignant tumors, including cholangiocarcinoma (CC). Tumor necrosis factor …

The reason for and consequences of BCL2L10 down‐regulation in gastric carcinoma are
poorly understood. Our aim was to investigate the function of the protein BCL2L10 in gastric …

Abstract Background/Aims: The detoxification enzyme AKR1B10, a member of the aldo‐keto
reductase superfamily, is discussed as a new biomarker candidate for hepatocellular …

Infection by Clonorchis sinensis, the Chinese or oriental liver fluke, is a significant risk factor
for the development of cholangiocarcinoma, a human epithelial carcinoma of the …

The acquisition of invasive functions by tumor cells is a first and crucial step toward the
development of metastasis, which nowadays represents the main cause of cancer-related …

Abstract Background/Aims: The mammalian target of rapamycin (mTOR) inhibitors play a
key role in regulating signal transduction by blocking the mTOR pathway and combining …