Artemisinin‐based combination therapy for treating uncomplicated malaria

D Sinclair, B Zani, S Donegan… - Cochrane Database …, 2009 - cochranelibrary.com
Background The World Health Organization recommends uncomplicated P. falciparum
malaria is treated using Artemisinin‐based Combination Therapy (ACT). This review aims to …

Malaria chemotherapeutics part I: History of antimalarial drug development, currently used therapeutics, and drugs in clinical development

M Schlitzer - ChemMedChem: Chemistry Enabling Drug …, 2007 - Wiley Online Library
Since ancient times, humankind has had to struggle against the persistent onslaught of
pathogenic microorganisms. Nowadays, malaria is still the most important infectious disease …

[HTML][HTML] Therapeutic efficacy of artemether-lumefantrine, artesunate-amodiaquine and dihydroartemisinin-piperaquine in the treatment of uncomplicated Plasmodium …

K Marwa, A Kapesa, V Baraka, E Konje, B Kidenya… - PloS one, 2022 - journals.plos.org
Background Sub-Saharan Africa has the highest burden of malaria in the world. Artemisinin-
based combination therapies (ACTs) have been the cornerstone in the efforts to reduce the …

Antimalarial drugs–what is in use and what is in the pipeline

M Schlitzer - Archiv der Pharmazie: An International Journal …, 2008 - Wiley Online Library
Malaria continues to be a potentially fatal threat to almost half of the world's population. In
light of this threat, the armory to fight this disease is rather limited. Resistance against the …

Malaria and artemisinin derivatives: an updated review

M Tayyab Ansari, Z Saeed Saify… - Mini reviews in …, 2013 - ingentaconnect.com
Malaria is the world's most prevalent disease that affects 515-600 million people each year
and about 40% of the world's population live at risk for this infection. The prevalence of …

Randomized comparison of amodiaquine plus sulfadoxine-pyrimethamine, artemether-lumefantrine, and dihydroartemisinin-piperaquine for the treatment of …

I Zongo, G Dorsey, N Rouamba… - Clinical Infectious …, 2007 - academic.oup.com
Background. Combination antimalarial therapy is advocated to improve treatment efficacy
and limit selection of drug-resistant parasites. We compared the efficacies of 3 combination …

Innovative high-performance liquid chromatography method development for the screening of 19 antimalarial drugs based on a generic approach, using design of …

B Debrus, P Lebrun, JM Kindenge, F Lecomte… - … of Chromatography A, 2011 - Elsevier
An innovative methodology based on design of experiments (DoE), independent component
analysis (ICA) and design space (DS) was developed in previous works and was tested out …

[图书][B] Applications of targeted nano drugs and delivery systems: nanoscience and nanotechnology in drug delivery

S Mohapatra, S Ranjan, N Dasgupta, S Thomas… - 2018 - books.google.com
Applications of Targeted Nano-Drugs and Delivery Systems: Nanoscience and
Nanotechnology in Drug Delivery explores the applications of Nano-drugs and their delivery …

[HTML][HTML] Improving educational achievement and anaemia of school children: design of a cluster randomised trial of school-based malaria prevention and enhanced …

S Brooker, G Okello, K Njagi, MM Dubeck, KE Halliday… - Trials, 2010 - Springer
Background Improving the health of school-aged children can yield substantial benefits for
cognitive development and educational achievement. However, there is limited …

[HTML][HTML] Efficacy of non-artemisinin-and artemisinin-based combination therapies for uncomplicated falciparum malaria in Cameroon

SY Whegang, R Tahar, VN Foumane, G Soula, H Gwét… - Malaria Journal, 2010 - Springer
Background The use of drug combinations, including non-artemisinin-based and artemisinin-
based combination therapy (ACT), is a novel strategy that enhances therapeutic efficacy and …