Developmental trajectories of early life stress and trauma: a narrative review on neurobiological aspects beyond stress system dysregulation

A Agorastos, P Pervanidou, GP Chrousos… - Frontiers in …, 2019 - frontiersin.org
Early life stressors display a high universal prevalence and constitute a major public health
problem. Prolonged psychoneurobiological alterations as sequelae of early life stress (ELS) …

Sex differences in the hypothalamic–pituitary–adrenal axis' response to stress: an important role for gonadal hormones

AL Heck, RJ Handa - Neuropsychopharmacology, 2019 - nature.com
The hypothalamic–pituitary–adrenal (HPA) axis, a neuroendocrine network that controls
hormonal responses to internal and external challenges in an organism's environment …

Sex differences and stress across the lifespan

TL Bale, CN Epperson - Nature neuroscience, 2015 - nature.com
Sex differences in stress responses can be found at all stages of life and are related to both
the organizational and activational effects of gonadal hormones and to genes on the sex …

The origins of neuroticism

DH Barlow, KK Ellard, S Sauer-Zavala… - Perspectives on …, 2014 - journals.sagepub.com
In this article, we provide a fresh perspective on the developmental origins of neuroticism—a
dimension of temperament marked by elevated stress reactivity resulting in the frequent …

[HTML][HTML] Animal models of anxiety disorders and stress

AC Campos, MV Fogaça, DC Aguiar… - Brazilian Journal of …, 2013 - SciELO Brasil
Anxiety and stress-related disorders are severe psychiatric conditions that affect
performance in daily tasks and represent a high cost to public health. The initial observation …

The hypothalamic-pituitary-adrenal axis in PTSD: Pathophysiology and treatment interventions

BW Dunlop, A Wong - Progress in Neuro-psychopharmacology and …, 2019 - Elsevier
Questions of how altered functioning of the hypothalamic pituitary adrenal (HPA) axis
contribute to the development and maintenance of posttraumatic stress disorder (PTSD) …

Why is obesity such a problem in the 21st century? The intersection of palatable food, cues and reward pathways, stress, and cognition

MJ Morris, JE Beilharz, J Maniam, AC Reichelt… - Neuroscience & …, 2015 - Elsevier
Abstract Changes in food composition and availability have contributed to the dramatic
increase in obesity over the past 30–40 years in developed and, increasingly, in developing …

Distinguishing differential susceptibility from diathesis–stress: Recommendations for evaluating interaction effects

GI Roisman, DA Newman, RC Fraley… - Development and …, 2012 - cambridge.org
This report describes the state of the art in distinguishing data generated by differential
susceptibility from diathesis–stress models. We discuss several limitations of existing …

Acute stressors and cortisol responses: a theoretical integration and synthesis of laboratory research.

SS Dickerson, ME Kemeny - Psychological bulletin, 2004 - psycnet.apa.org
This meta-analysis reviews 208 laboratory studies of acute psychological stressors and tests
a theoretical model delineating conditions capable of eliciting cortisol responses …

The role of childhood trauma in the neurobiology of mood and anxiety disorders: preclinical and clinical studies

C Heim, CB Nemeroff - Biological psychiatry, 2001 - Elsevier
Epidemiologic studies indicate that children exposed to early adverse experiences are at
increased risk for the development of depression, anxiety disorders, or both. Persistent …