Tunable metal–organic frameworks assist in catalyzing DNAzymes with amplification platforms for biomedical applications

X Zhu, J Xu, G Ling, P Zhang - Chemical Society Reviews, 2023 - pubs.rsc.org
Various binding modes of tunable metal organic frameworks (MOFs) and functional
DNAzymes (Dzs) synergistically catalyze the emergence of abundant functional …

Recent advancements in the formulation of nanomaterials-based nanozymes, their catalytic activity, and biomedical applications

S Singh, N Rai, H Tiwari, P Gupta, A Verma… - ACS Applied Bio …, 2023 - ACS Publications
Nanozymes are nanoparticles with intrinsic enzyme-mimicking properties that have become
more prevalent because of their ability to outperform conventional enzymes by overcoming …

Dual active centers linked by a reversible electron station as a multifunctional nanozyme to induce synergetically enhanced cascade catalysis for tumor-specific …

Q Zhao, L Zheng, Y Gao, J Li, J Wei… - Journal of the …, 2023 - ACS Publications
Nanozymes have shown great promise in reactive oxygen species (ROS)-mediated tumor
therapy with mitigated side effects but are normally limited by the complex tumor …

Nanozyme-based remodeling of disease microenvironments for disease prevention and treatment: a review

Y Ju, X Liu, X Ye, M Dai, B Fang… - ACS Applied Nano …, 2023 - ACS Publications
Nanomaterials that can mimic the activity of various enzymes have been studied extensively
in the biomedical field in recent years. Nanozymes offer better stability and economic value …

Smart nanozymes for cancer therapy: the next frontier in oncology

N Pn, S Mehla, A Begum, HK Chaturvedi… - Advanced …, 2023 - Wiley Online Library
Nanomaterials that mimic the catalytic activity of natural enzymes in the complex biological
environment of the human body are called nanozymes. Recently, nanozyme systems have …

[HTML][HTML] Piezoelectric enhanced sulfur doped graphdiyne nanozymes for synergistic ferroptosis–apoptosis anticancer therapy

J Wang, Y Chu, Z Zhao, C Zhang, Q Chen… - Journal of …, 2023 - Springer
Graphdiyne has excellent potential due to its enzymatic properties. Metal-free sulfur-doped
Graphdiyne (S-GDY) has piezoelectric characteristics, and ultrasonic excitation of S-GDY …

Targeting tumor microenvironment by metal peroxide nanoparticles in cancer therapy

SN Mbugua - Bioinorganic Chemistry and Applications, 2022 - Wiley Online Library
Solid tumors have a unique tumor microenvironment (TME), which includes hypoxia, low
acidity, and high hydrogen peroxide and glutathione (GSH) levels, among others. These …

Recent advances in metal-organic frameworks for stimuli-responsive drug delivery

F Xing, J Xu, Y Zhou, P Yu, M Zhe, Z Xiang, X Duan… - Nanoscale, 2024 - pubs.rsc.org
After entering the human body, drugs for treating diseases are affected by various factors,
which are prone to delivery and release in an uncontrolled manner. Based on this, many …

[HTML][HTML] Tumor microenvironment responsive metal nanoparticles in cancer immunotherapy

R Yang, L Chen, Y Wang, L Zhang, X Zheng… - Frontiers in …, 2023 - frontiersin.org
Malignant tumors have a unique tumor microenvironment (TME), which includes mild acidity,
hypoxia, overexpressed reactive oxygen species (ROS), and high glutathione (GSH) levels …

Metal organic framework–based variable-size nanoparticles for tumor microenvironment-responsive drug delivery

Y Wang, N Gao, X Li, G Ling, P Zhang - Drug Delivery and Translational …, 2024 - Springer
Nanoparticles (NPs) have been designed for the treatment of tumors increasingly. However,
the drawbacks of single-size NPs are still worth noting, as their circulation and metabolism in …