The outcome of Mycobacterium tuberculosis (Mtb) infection ranges from a complete
pathogen clearance through asymptomatic latent infection (LTBI) to active tuberculosis (TB) …

The view of CD4 T‐cell‐mediated immunity as a balance between distinct lineages of Th1
and Th2 cells has changed dramatically. Identification of the IL‐17 family of cytokines and of …

Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are classified as two
lung complications arising from various conditions such as sepsis, trauma, and lung …

Psoriasis is a skin disease where various cytokines play a detrimental role, yet our
understanding of the disease is still limited. TNF is a validated drug target in psoriasis and …

Background and purpose Alzheimer's disease (AD) is a common neurodegenerative
disease characterized by a neuroinflammatory state, and to date, there is no cure and its …

NLRP3 inflammasome activation is implicated in the pathogenesis of a wide range of
inflammatory diseases, but medications targeting the NLRP3 inflammasome are not …

Injury triggers inflammatory responses and tissue repair. Several treatments are currently in
use to accelerate healing; however, more efficient formulations are still needed for specific …

One of the hallmarks of COVID-19 is the cytokine storm that provokes primarily pneumonia
followed by systemic inflammation. Emerging evidence has identified a potential link …

The immune system is closely linked to human metabolic diseases. Serum levels of IL-6
increase with obesity and insulin resistance. Not only does IL-6 decrease the insulin …

Gout is a paradigm of acute, self-limiting inflammation caused by the deposition of
monosodium urate (MSU) crystals within intra-and/or peri-articular areas, leading to …