SCN5A channelopathy: arrhythmia, cardiomyopathy, epilepsy and beyond
CA Remme - … Transactions of the Royal Society B, 2023 - royalsocietypublishing.org
Influx of sodium ions through voltage-gated sodium channels in cardiomyocytes is essential
for proper electrical conduction within the heart. Both acquired conditions associated with …
for proper electrical conduction within the heart. Both acquired conditions associated with …
Implantable defibrillators in primary prevention of genetic arrhythmias. A shocking choice?
Many previously unexplained life-threatening ventricular arrhythmias and sudden cardiac
deaths (SCDs) in young individuals are now recognized to be genetic in nature and are …
deaths (SCDs) in young individuals are now recognized to be genetic in nature and are …
Pathogenesis and management of Brugada syndrome: recent advances and protocol for umbrella reviews of meta-analyses in major arrhythmic events risk …
HM Aziz, MP Zarzecki, S Garcia-Zamora… - Journal of Clinical …, 2022 - mdpi.com
Brugada syndrome (BrS) is a primary electrical disease associated with life-threatening
arrhythmias. It is estimated to cause at least 20% of sudden cardiac deaths (SCDs) in …
arrhythmias. It is estimated to cause at least 20% of sudden cardiac deaths (SCDs) in …
Brugada syndrome: more than a monogenic channelopathy
Brugada syndrome (BrS) is an inherited cardiac channelopathy first diagnosed in 1992 but
still considered a challenging disease in terms of diagnosis, arrhythmia risk prediction …
still considered a challenging disease in terms of diagnosis, arrhythmia risk prediction …
Patient-specific iPSC-derived cardiomyocytes reveal aberrant activation of Wnt/β-catenin signaling in SCN5A-related Brugada syndrome
D Cai, X Wang, Y Sun, H Fan, J Zhou, Z Yang… - Stem Cell Research & …, 2023 - Springer
Background Mutations in the cardiac sodium channel gene SCN5A cause Brugada
syndrome (BrS), an arrhythmic disorder that is a leading cause of sudden death and lacks …
syndrome (BrS), an arrhythmic disorder that is a leading cause of sudden death and lacks …
Prediction of the presence of ventricular fibrillation from a Brugada electrocardiogram using artificial intelligence
T Nakamura, T Aiba, W Shimizu, T Furukawa… - Circulation …, 2023 - jstage.jst.go.jp
Background: Brugada syndrome is a potential cause of sudden cardiac death (SCD) and is
characterized by a distinct ECG, but not all patients with A Brugada ECG develop SCD. In …
characterized by a distinct ECG, but not all patients with A Brugada ECG develop SCD. In …
Noncoding RNAs and Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes in Cardiac Arrhythmic Brugada Syndrome
B Theisen, A Holtz, V Rajagopalan - Cells, 2023 - mdpi.com
Hundreds of thousands of people die each year as a result of sudden cardiac death, and
many are due to heart rhythm disorders. One of the major causes of these arrhythmic events …
many are due to heart rhythm disorders. One of the major causes of these arrhythmic events …
Historical perspective and recent progress in cardiac ion channelopathies research and clinical practice in Hong Kong
Cardiac ion channelopathies encompass a set of inherited or acquired conditions that are
due to dysfunction in ion channels or their associated proteins, typically in the presence of …
due to dysfunction in ion channels or their associated proteins, typically in the presence of …
The psychological impact of receiving a Brugada syndrome diagnosis
C van der Werf, PG Postema - Europace, 2023 - academic.oup.com
psychological impact of receiving a Brugada syndrome diagnosis | EP Europace | Oxford
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Academic Skip to Main Content Advertisement intended for healthcare professionals Oxford …
Unravelling Novel SCN5A Mutations Linked to Brugada Syndrome: Functional, Structural, and Genetic Insights
A Frosio, E Micaglio, I Polsinelli, S Calamaio… - International Journal of …, 2023 - mdpi.com
Brugada Syndrome (BrS) is a rare inherited cardiac arrhythmia causing potentially fatal
ventricular tachycardia or fibrillation, mainly occurring during rest or sleep in young …
ventricular tachycardia or fibrillation, mainly occurring during rest or sleep in young …