Advanced optoacoustic methods for multiscale imaging of in vivo dynamics

XL Deán-Ben, S Gottschalk, B Mc Larney… - Chemical Society …, 2017 - pubs.rsc.org
Visualization of dynamic functional and molecular events in an unperturbed in vivo
environment is essential for understanding the complex biology of living organisms and of …

Rapid volumetric optoacoustic imaging of neural dynamics across the mouse brain

S Gottschalk, O Degtyaruk, B Mc Larney… - Nature biomedical …, 2019 - nature.com
Efforts to scale neuroimaging towards the direct visualization of mammalian brain-wide
neuronal activity have faced major challenges. Although high-resolution optical imaging of …

Spiral volumetric optoacoustic tomography visualizes multi-scale dynamics in mice

XL Deán-Ben, TF Fehm, SJ Ford, S Gottschalk… - Light: Science & …, 2017 - nature.com
Imaging dynamics at different temporal and spatial scales is essential for understanding the
biological complexity of living organisms, disease state and progression. Optoacoustic …

Non-invasive determination of murine placental and foetal functional parameters with multispectral optoacoustic tomography

K Basak, X Luís Deán-Ben, S Gottschalk… - Light: Science & …, 2019 - nature.com
Despite the importance of placental function in embryonic development, it remains poorly
understood and challenging to characterize, primarily due to the lack of non-invasive …

Investigating fibroblast cells under “safe” and “injurious” blue‐light exposure by holographic microscopy

A Calabuig, M Mugnano, L Miccio, S Grilli… - Journal of …, 2017 - Wiley Online Library
The exposure to visible light has been shown to exert various biological effects, such as
erythema and retinal degeneration. However, the phototoxicity mechanisms in living cells …

Isolated murine brain model for large-scale optoacoustic calcium imaging

S Gottschalk, O Degtyaruk, B Mc Larney… - Frontiers in …, 2019 - frontiersin.org
Real-time visualization of large-scale neural dynamics in whole mammalian brains is
hindered with existing neuroimaging methods having limited capacity when it comes to …

High-throughput platform for optoacoustic probing of genetically encoded calcium ion indicators

UAT Hofmann, A Fabritius, J Rebling, H Estrada… - Iscience, 2019 - cell.com
Functional optoacoustic (OA) imaging assisted with genetically encoded calcium ion
indicators (GECIs) holds promise for imaging large-scale neuronal activity at depths and …

Temperature dependence of photoacoustic signal from contrast dyes and its application to signal enhancement in stained samples

A Thomas, SS Mayanglambam - TENCON 2019-2019 IEEE …, 2019 - ieeexplore.ieee.org
We report our study on temperature dependence of photoacoustic signal from contrast dye
and this technique is used to enhance signal strength from stained biological samples. A …

Functional Optoacoustic Imaging

D Razansky - Handbook of Neurophotonics, 2020 - taylorfrancis.com
Promising new developments include the introduction of near-infrared-shifted fluorescent
molecules that can be used for in vivo labeling of deep tissue functional and molecular …

Rapid Optoacoustic Imaging for Neurology, Cardiology and Vascular Biology

JJ Rebling - 2019 - mediatum.ub.tum.de
Optoacoustic imaging offers minimally invasive, fast, and volumetric visualization of cells,
organs and organisms based on the detection of light-induced ultrasound waves. While …