Control of sex development
A Biason-Lauber - Best practice & research Clinical endocrinology & …, 2010 - Elsevier
The process of sexual differentiation is central for reproduction of almost all metazoan, and
therefore, for maintenance of practically all multicellular organisms. In sex development, we …
therefore, for maintenance of practically all multicellular organisms. In sex development, we …
Disorders of sex development with testicular differentiation in SRY-negative 46, XX individuals: clinical and genetic aspects
RP Grinspon, RA Rey - Sexual Development, 2016 - karger.com
Virilisation of the XX foetus is the result of androgen excess, resulting most frequently from
congenital adrenal hyperplasia in individuals with typical ovarian differentiation. In rare …
congenital adrenal hyperplasia in individuals with typical ovarian differentiation. In rare …
[HTML][HTML] Molecular characterization of XX maleness
RP Grinspon, RA Rey - International Journal of Molecular Sciences, 2019 - mdpi.com
Androgens and anti-Müllerian hormone (AMH), secreted by the foetal testis, are responsible
for the development of male reproductive organs and the regression of female anlagen …
for the development of male reproductive organs and the regression of female anlagen …
Sex determination and disorders of sex development according to the revised nomenclature and classification in 46, XX individuals
E Kousta, A Papathanasiou, N Skordis - Hormones, 2010 - Springer
There have been considerable advances concerning understanding of the early and later
stages of ovarian development; a number of genes have been implicated and their …
stages of ovarian development; a number of genes have been implicated and their …
The long-term followup of 33 cases of true hermaphroditism: a 40-year experience with conservative gonadal surgery
G Verkauskas, F Jaubert, S Lortat-Jacob, V Malan… - The Journal of …, 2007 - Elsevier
PURPOSE: Little is known about long-term outcomes of conservative gonadal surgery in
true hermaphroditism. We present our experience with evaluation and treatment of a large …
true hermaphroditism. We present our experience with evaluation and treatment of a large …
Turning on the male–SRY, SOX9 and sex determination in mammals
KC Knower, S Kelly, VR Harley - Cytogenetic and Genome Research, 2003 - karger.com
The decision of the bi-potential gonad to develop into either a testis or ovary is determined
by the presence or absence of the Sex-determining Region gene on the Y chromosome …
by the presence or absence of the Sex-determining Region gene on the Y chromosome …
Long‐term outcome of ovotesticular disorder of sex development: A single center experience
F Matsui, K Shimada, F Matsumoto… - … Journal of Urology, 2011 - Wiley Online Library
Objectives: To describe the clinical features of children with ovotesticular disorder of sex
development (DSD) and to review cases of ovotesticular DSD in Japan. Methods: Medical …
development (DSD) and to review cases of ovotesticular DSD in Japan. Methods: Medical …
The spectrum of ovotesticular disorders of sex development in South Africa: a single-centre experience
Y Ganie, C Aldous, Y Balakrishna… - Hormone research in …, 2017 - karger.com
Objective: To describe the clinical characteristics, biochemistry, histopathology, and long-
term outcomes in subjects with ovotesticular (OT) disorder of sex development (DSD). Study …
term outcomes in subjects with ovotesticular (OT) disorder of sex development (DSD). Study …
[HTML][HTML] True hermaphroditism and mixed gonadal dysgenesis in young children: a clinicopathologic study of 10 cases
KR Kim, Y Kwon, JY Joung, KS Kim, AG Ayala, JY Ro - Modern Pathology, 2002 - Elsevier
True hermaphroditism (TH) refers to individuals who have both unequivocal ovarian tissue
and testicular elements regardless of their karyotypes; whereas mixed gonadal dysgenesis …
and testicular elements regardless of their karyotypes; whereas mixed gonadal dysgenesis …
Disorders of sex development
V Arboleda, E Vilain - Genetic diagnosis of endocrine disorders, 2016 - Elsevier
Disorders of sex development (DSD) are rare disorders occurring when there is a
discordance between chromosomal, gonadal, or phenotypic sex. These occur in the …
discordance between chromosomal, gonadal, or phenotypic sex. These occur in the …