Purpose Angiogenesis has been studied in pituitary neuroendocrine tumours (PitNETs), but
the role of the tumour microenvironment (TME) in regulating PitNET angiogenesis remains …

Non-functioning pituitary carcinomas (NFPC) are defined as tumours of adenophyseal origin
with craniospinal or systemic dissemination, with the absence of a hormonal hypersecretion …

Cancer immunotherapy is a breakthrough strategy entwined with toxicity. Immune-related
hypophysitis is conventionally considered distinctive of cytotoxic T-lymphocyte antigen 4 …

The use of temozolomide (TMZ) for the management of aggressive pituitary tumours (APT)
has revolutionised clinical practice in this field with significantly improved clinical outcomes …

Human pituitary adenomas are one of the most common intracranial neoplasms. Although
most of these tumors are benign and can be treated medically or by transsphenoidal …

Context Pituitary adenoma (PA) is a common intracranial tumor. The evidence indicates that
the tumor immune microenvironment (TIME) is associated with PA and that the intestinal …

Simple Summary The biological behavior of Pituitary Neuroendocrine Tumors (PitNET)
remains unclear. Many efforts have been performed in order to clarify this point. The …

Purpose Pituitary tumors are the second most common primary brain tumors. Functional
tumors demonstrate increased PD-L1 expression, but expression of other checkpoint …

Neuroendocrine tumours of the adenohypophysis have traditionally been designated as
pituitary adenomas to underline their usually indolent growth and lack of metastatic …

CONCLUSION: APA is a tumor with frequent recurrence and a short median expected length
of survival. Here, we demonstrate the utility of immunotherapy in a single case report of APA …