Genetic polymorphisms in DNA repair genes OGG1, APE1, XRCC1, and XPD and the risk of age-related cataract
Y Zhang, L Zhang, Z Song, DL Sun, HR Liu, SB Fu… - Ophthalmology, 2012 - Elsevier
PURPOSE: To analyze the association of the polymorphisms in 8-oxoguanine glycosylase-1
(OGG1), X-ray repair cross-complementing-1 (XRCC1), and AP endonuclease-1 (APE1) …
(OGG1), X-ray repair cross-complementing-1 (XRCC1), and AP endonuclease-1 (APE1) …
Molecular characterization of the human lens epithelium-derived cell line SRA01/04
BAT Weatherbee, JR Barton, AD Siddam… - Experimental eye …, 2019 - Elsevier
Cataract-associated gene discovery in human and animal models have informed on key
aspects of human lens development, homeostasis and pathology. Additionally, in vitro …
aspects of human lens development, homeostasis and pathology. Additionally, in vitro …
[HTML][HTML] HSF4 is involved in DNA damage repair through regulation of Rad51
X Cui, J Zhang, R Du, L Wang, S Archacki… - … et Biophysica Acta (BBA …, 2012 - Elsevier
Heat shock factor protein 4 (HSF4) is expressed exclusively in the ocular lens and plays a
critical role in the lens formation and differentiation. Mutations in the HSF4 gene lead to …
critical role in the lens formation and differentiation. Mutations in the HSF4 gene lead to …
A class I (Senofilcon A) soft contact lens prevents UVB-induced ocular effects, including cataract, in the rabbit in vivo
FJ Giblin, LR Lin, VR Leverenz… - … ophthalmology & visual …, 2011 - iovs.arvojournals.org
Purpose.: UVB radiation from sunlight is known to be a risk factor for human cataract. The
purpose in this study was to investigate the ability of a class I UV-blocking soft contact lens to …
purpose in this study was to investigate the ability of a class I UV-blocking soft contact lens to …
Polymorphisms of DNA repair genes in endometrial cancer
A Sobczuk, T Poplawski, J Blasiak - Pathology & Oncology Research, 2012 - Springer
Endometrial cancer belongs to the commonest malignancy in females. Its development may
be associated with the high exposure of endometrium to exo-and endogenous estrogens …
be associated with the high exposure of endometrium to exo-and endogenous estrogens …
Polymorphisms of the DNA repair genes XPD and XRCC1 and the risk of age-related macular degeneration
Purpose.: Oxidative stress seems to be an important factor in the development of age-related
macular degeneration (AMD). The role of DNA repair mechanisms has also received …
macular degeneration (AMD). The role of DNA repair mechanisms has also received …
Polymorphisms of the Homologous Recombination Gene RAD51 in Keratoconus and Fuchs Endothelial Corneal Dystrophy
E Synowiec, KA Wojcik, J Izdebska, E Binczyk… - Disease …, 2013 - Wiley Online Library
Purpose. We investigated the association between genotypes and haplotypes of the c.‐
61G> T (rs 1801320) and c.‐98G> C (rs 1801321) polymorphisms of the RAD51 gene and …
61G> T (rs 1801320) and c.‐98G> C (rs 1801321) polymorphisms of the RAD51 gene and …
DNA repair gene XPD and XRCC1 polymorphisms and the risk of febrile neutropenia and mucositis in children with leukemia and lymphoma
The aim of the study is to investigate association between DNA repair gene XPD and
XRCC1 polymorphisms and febrile neutropenia (FN) and mucositis. The study population …
XRCC1 polymorphisms and febrile neutropenia (FN) and mucositis. The study population …
The value of XPD and XRCC1 genotype polymorphisms to predict clinical outcome in metastatic colorectal carcinoma patients with irinotecan-based regimens
Background Previous studies have suggested that DNA repair enzyme polymorphisms may
bear prognostic value in metastatic colorectal carcinoma (MCRC). Methods We …
bear prognostic value in metastatic colorectal carcinoma (MCRC). Methods We …