[HTML][HTML] Impacts of cigarette smoking on immune responsiveness: Up and down or upside down?
F Qiu, CL Liang, H Liu, YQ Zeng, S Hou, S Huang… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Cigarette smoking is associated with numerous diseases and poses a serious challenge to
the current healthcare system worldwide. Smoking impacts both innate and adaptive …
the current healthcare system worldwide. Smoking impacts both innate and adaptive …
New insights into the immunology of chronic obstructive pulmonary disease
GG Brusselle, GF Joos, KR Bracke - The Lancet, 2011 - thelancet.com
Chronic obstructive pulmonary disease (COPD) is a heterogeneous syndrome associated
with abnormal inflammatory immune responses of the lung to noxious particles and gases …
with abnormal inflammatory immune responses of the lung to noxious particles and gases …
The pathology of small airways disease in COPD: historical aspects and future directions
A Higham, AM Quinn, JED Cançado, D Singh - Respiratory research, 2019 - Springer
Small airways disease (SAD) is a cardinal feature of chronic obstructive pulmonary disease
(COPD) first recognized in the nineteenth century. The diverse histopathological features …
(COPD) first recognized in the nineteenth century. The diverse histopathological features …
Immune dysfunction in patients with chronic obstructive pulmonary disease
TA Bhat, L Panzica, SG Kalathil… - Annals of the American …, 2015 - atsjournals.org
Chronic obstructive pulmonary disease (COPD) is a complex chronic disease. Chronic
inflammation is the hallmark of COPD, involving the interplay of a wide variety of cells in the …
inflammation is the hallmark of COPD, involving the interplay of a wide variety of cells in the …
T-Regulatory Cells and Programmed Death 1+ T Cells Contribute to Effector T-Cell Dysfunction in Patients with Chronic Obstructive Pulmonary Disease
SG Kalathil, AA Lugade, V Pradhan… - American journal of …, 2014 - atsjournals.org
Rationale: Previous studies from our laboratory have shown that peripheral blood
mononuclear cells (PBMCs) from patients with chronic obstructive pulmonary disease …
mononuclear cells (PBMCs) from patients with chronic obstructive pulmonary disease …
[HTML][HTML] Th17/Treg imbalance in chronic obstructive pulmonary disease: clinical and experimental evidence
The imbalance between pro-and anti-inflammatory immune responses mediated by Th17
and Treg cells is deeply involved in the development and progression of inflammation in …
and Treg cells is deeply involved in the development and progression of inflammation in …
Inflammatory changes in the airways of mice caused by cigarette smoke exposure are only partially reversed after smoking cessation
S Braber, PAJ Henricks, FP Nijkamp, AD Kraneveld… - Respiratory …, 2010 - Springer
Background Tobacco smoking irritates and damages the respiratory tract and contributes to
a higher risk of developing lung emphysema. At present, smoking cessation is the only …
a higher risk of developing lung emphysema. At present, smoking cessation is the only …
Combined pulmonary fibrosis and emphysema in scleroderma‐related lung disease has a major confounding effect on lung physiology and screening for pulmonary …
KM Antoniou, GA Margaritopoulos… - Arthritis & …, 2016 - Wiley Online Library
Objective To assess the prevalence of combined pulmonary fibrosis and emphysema
(CPFE) in systemic sclerosis (SSc) patients with interstitial lung disease (ILD) and the effect …
(CPFE) in systemic sclerosis (SSc) patients with interstitial lung disease (ILD) and the effect …
Identification of cells expressing IL-17A and IL-17F in the lungs of patients with COPD
A Eustace, LJC Smyth, L Mitchell, K Williamson… - Chest, 2011 - Elsevier
Background Lymphocytes secrete IL-17A and IL-17F, which enhance innate immune
responses. IL-17 expression has not been studied in COPD small airways. The aim of this …
responses. IL-17 expression has not been studied in COPD small airways. The aim of this …
The effect of peroxisome proliferator-activated receptor-γ ligands on in vitro and in vivo models of COPD
S Lea, J Plumb, H Metcalfe, D Spicer… - European …, 2014 - Eur Respiratory Soc
Peroxisome proliferator-activated receptor (PPAR)-γ is expressed in alveolar macrophages.
The anti-inflammatory potential of the PPAR-γ ligands rosiglitazone and pioglitazone were …
The anti-inflammatory potential of the PPAR-γ ligands rosiglitazone and pioglitazone were …