Evasion of COPD in smokers: at what price?
MG Cosio, M Saetta - European Respiratory Journal, 2012 - Eur Respiratory Soc
Investigations toward the understanding of chronic obstructive pulmonary disease (COPD)
have been directed, so far, to the study of mechanisms leading to the disease. We believe …
have been directed, so far, to the study of mechanisms leading to the disease. We believe …
Neutral sphingomyelinase-2, acid sphingomyelinase, and ceramide levels in COPD patients compared to controls
SR Lea, HJ Metcalfe, J Plumb, C Beerli… - … journal of chronic …, 2016 - Taylor & Francis
Background Increased pulmonary ceramide levels are suggested to play a causative role in
lung diseases including COPD. Neutral sphingomyelinase-2 (nSMase-2) and acid SMase …
lung diseases including COPD. Neutral sphingomyelinase-2 (nSMase-2) and acid SMase …
Increased CTLA‐4+ T cells may contribute to impaired T helper type 1 immune responses in patients with chronic obstructive pulmonary disease
DBA Tan, TH Teo, AM Setiawan, NE Ong… - …, 2017 - Wiley Online Library
Impaired T helper type 1 (Th1) function is implicated in the susceptibility of patients with
chronic obstructive pulmonary disease (COPD) to respiratory infections, which are common …
chronic obstructive pulmonary disease (COPD) to respiratory infections, which are common …
Age-related activation of MKK/p38/NF-κB signaling pathway in lung: From mouse to human
X Ren, H Du, Y Li, X Yao, J Huang, Z Li, W Wang… - Experimental …, 2014 - Elsevier
We and others previously reported that the pro-inflammatory cytokine tumor necrosis factor-α
(TNF-α), interleukin-1β (IL-1β) and IL-6 significantly accumulate with age in mouse lung …
(TNF-α), interleukin-1β (IL-1β) and IL-6 significantly accumulate with age in mouse lung …
The clinical association of programmed death-1/PD-L1 axis, myeloid derived suppressor cells subsets and regulatory T cells in peripheral blood of stable COPD …
M Zhang, Y Wan, J Han, J Li, H Gong, X Mu - PeerJ, 2024 - peerj.com
Background Myeloid-derived suppressor cells (MDSCs) have crucial immunosuppressive
role in T cell dysfunction in various disease processes. However, the role of MDSCs and …
role in T cell dysfunction in various disease processes. However, the role of MDSCs and …
Immunology of chronic obstructive pulmonary disease and sulfur mustard induced airway injuries: implications for immunotherapeutic interventions
Y Panahi, F Jadidi-Niaragh… - Current …, 2016 - ingentaconnect.com
Background: Sulfur mustard (SM)-induced airway injuries and chronic obstructive pulmonary
disease (COPD) are characterized by chronic inflammation of the respiratory tract and share …
disease (COPD) are characterized by chronic inflammation of the respiratory tract and share …
Regulatory T cells and COPD
R Dancer, DM Sansom - Thorax, 2013 - thorax.bmj.com
While the innate immune system has long been implicated in the pathogenesis of COPD, a
role for the acquired immune system is less well studied. The increasing recognition that …
role for the acquired immune system is less well studied. The increasing recognition that …
Increased T-regulatory cells in lungs and draining lymph nodes in a murine model of COPD
T Demoor, KR Bracke, GF Joos… - European Respiratory …, 2010 - Eur Respiratory Soc
The characterisation of regulatory T (Treg) cells in chronic obstructive pulmonary disease
(COPD) has become of particular interest considering the recent reports on adaptive …
(COPD) has become of particular interest considering the recent reports on adaptive …
[HTML][HTML] 调节性T 细胞在烟熏诱导的小鼠肺气肿模型中的变化及意义
赵考昌， 陈雪芹， 陈国忠 - 武汉大学学报(医学版), 2017 - xml-data.org
目的: 研究CD4+ Foxp3+ 调节性T 细胞在烟熏诱导的小鼠肺气肿模型中的变化并探讨其意义.
方法: 6-8 周龄C57BL/6 FoxP3-GFP knock-in 小鼠18 只, 按照随机对照方法分为吸烟组(S 组) …
方法: 6-8 周龄C57BL/6 FoxP3-GFP knock-in 小鼠18 只, 按照随机对照方法分为吸烟组(S 组) …