[PDF][PDF] Iron and diabetes risk

JA Simcox, DA McClain - Cell metabolism, 2013 - cell.com
Iron overload is a risk factor for diabetes. The link between iron and diabetes was first
recognized in pathologic conditions—hereditary hemochromatosis and thalassemia—but …

Cross-talk between iron metabolism and diabetes

JM Fernández-Real, A López-Bermejo, W Ricart - Diabetes, 2002 - Am Diabetes Assoc
Emerging scientific evidence has disclosed unsuspected influences between iron
metabolism and type 2 diabetes. The relationship is bi-directional—iron affects glucose …

Disordered iron homeostasis in chronic heart failure: prevalence, predictors, and relation to anemia, exercise capacity, and survival

DO Okonko, AKJ Mandal, CG Missouris… - Journal of the American …, 2011 - jacc.org
Objectives: The aim of this study was to comprehensively delineate iron metabolism and its
implications in patients with chronic heart failure (CHF). Background: Iron deficiency is an …

[HTML][HTML] Adipocyte iron regulates adiponectin and insulin sensitivity

JS Gabrielsen, Y Gao, JA Simcox… - The Journal of …, 2012 - Am Soc Clin Investig
Iron overload is associated with increased diabetes risk. We therefore investigated the effect
of iron on adiponectin, an insulin-sensitizing adipokine that is decreased in diabetic patients …

[HTML][HTML] Prevalence of anaemia in older persons: systematic review

H Gaskell, S Derry, R Andrew Moore, HJ McQuay - BMC geriatrics, 2008 - Springer
Background Ageing populations will impact on healthcare provision, especially since extra
years are not necessarily spent in good health. It is important to identify and understand the …

The role of iron in type 2 diabetes in humans

SN Rajpathak, JP Crandall, J Wylie-Rosett… - … et Biophysica Acta (BBA …, 2009 - Elsevier
The role of micronutrients in the etiology of type 2 diabetes is not well established. Several
lines of evidence suggest that iron play may a role in the pathogenesis of type 2 diabetes …

Effects of iron overload on chronic metabolic diseases

JM Fernández-Real, M Manco - The lancet Diabetes & …, 2014 - thelancet.com
Iron can affect the clinical course of several chronic metabolic diseases such as type 2
diabetes, obesity, non-alcoholic fatty liver disease, and atherosclerosis. Iron overload can …

Anemia in the elderly: current understanding and emerging concepts

R Eisenstaedt, BWJH Penninx, RC Woodman - Blood reviews, 2006 - Elsevier
Anemia is currently defined by the World Health Organization (WHO) as a hemoglobin (Hb)
level< 13 g/dL in men and< 12 g/dL in women. While estimates vary widely, nearly one …

[HTML][HTML] Iron and non-alcoholic fatty liver disease

LJ Britton, VN Subramaniam… - World journal of …, 2016 - ncbi.nlm.nih.gov
The mechanisms that promote liver injury in non-alcoholic fatty liver disease (NAFLD) are
yet to be thoroughly elucidated. As such, effective treatment strategies are lacking and novel …

[HTML][HTML] Effects of phlebotomy-induced reduction of body iron stores on metabolic syndrome: results from a randomized clinical trial

KS Houschyar, R Lüdtke, GJ Dobos, U Kalus… - BMC medicine, 2012 - Springer
Background Metabolic syndrome (METS) is an increasingly prevalent but poorly understood
clinical condition characterized by insulin resistance, glucose intolerance, dyslipidemia …