Far-East Asian Toxoplasma isolates share ancestry with North and South/Central American recombinant lineages

F Ihara, H Kyan, Y Takashima, F Ono… - Nature …, 2024 - nature.com
Toxoplasma gondii is a global protozoan pathogen. Clonal lineages predominate in Europe,
North America, Africa, and China, whereas highly recombinant parasites are endemic in …

The aromatic amino acid hydroxylase genes AAH1 and AAH2 in Toxoplasma gondii contribute to transmission in the cat

ZT Wang, SK Verma, JP Dubey, LD Sibley - PLoS pathogens, 2017 - journals.plos.org
The Toxoplasma gondii genome contains two aromatic amino acid hydroxylase genes,
AAH1 and AAH2 encode proteins that produce L-DOPA, which can serve as a precursor of …

Late embryogenesis abundant proteins contribute to the resistance of Toxoplasma gondii oocysts against environmental stresses

D Arranz-Solís, D Warschkau, BT Fabian, F Seeber… - Mbio, 2023 - Am Soc Microbiol
Toxoplasma gondii oocysts, which are shed in large quantities in the feces from infected
felines, are very stable in the environment, resistant to most inactivation procedures, and …

Highly contiguous genomes of human clinical isolates of Giardia duodenalis reveal assemblage- and sub-assemblage-specific presence–absence variation in …

C Klotz, MW Schmid, K Winter, R Ignatius… - Microbial …, 2023 - microbiologyresearch.org
Giardia duodenalis (syn. G. intestinalis, G. lamblia) is a widespread gastrointestinal
protozoan parasite with debated taxonomic status. Currently, eight distinct genetic sub …

A hotspot of Toxoplasma gondii Africa 1 lineage in Benin: How new genotypes from West Africa contribute to understand the parasite genetic diversity worldwide

A Hamidović, JR Etougbétché… - PLoS neglected …, 2021 - journals.plos.org
Through international trades, Europe, Africa and South America share a long history of
exchanges, potentially of pathogens. We used the worldwide parasite Toxoplasma gondii to …

Aminoglycerophospholipid flipping and P4-ATPases in Toxoplasma gondii

K Chen, Ö Günay-Esiyok, M Klingeberg… - Journal of Biological …, 2021 - ASBMB
Lipid flipping in the membrane bilayers is a widespread eukaryotic phenomenon that is
catalyzed by assorted P4-ATPases. Its occurrence, mechanism, and importance in …

Newly detected, virulent Toxoplasma gondii COUG strain causing fatal steatitis and toxoplasmosis in southern sea otters (Enhydra lutris nereis)

MA Miller, CA Newberry, DM Sinnott… - Frontiers in Marine …, 2023 - frontiersin.org
From February 2020 to March 2022, four southern sea otters (Enhydra lutris nereis) stranded
in California with severe protozoal steatitis and systemic toxoplasmosis. Three of the …

The Association of Toxoplasma gondii IgG and Cardiovascular Biomarkers

A Babekir, S Mostafa, E Obeng-Gyasi - International Journal of …, 2021 - mdpi.com
Background: Toxoplasma gondii (T. gondii) is a protozoan parasite with high prevalence
worldwide. More than 40 million individuals in the United States carry this parasite. T. gondii …

The introduction of new hosts with human trade shapes the extant distribution of Toxoplasma gondii lineages

L Galal, A Sarr, T Cuny, C Brouat… - PLoS Neglected …, 2019 - journals.plos.org
Toxoplasma gondii is a zoonotic protozoan with a worldwide occurrence, but the
determinants of the current pattern in the geographical distribution of T. gondii lineages and …

Diversity and evolution of sensor histidine kinases in eukaryotes

S Kabbara, A Hérivaux… - Genome biology and …, 2019 - academic.oup.com
Histidine kinases (HKs) are primary sensor proteins that act in cell signaling pathways
generically referred to as “two-component systems”(TCSs). TCSs are among the most widely …