Biodegradable polymeric nanoparticles for drug delivery to solid tumors

A Gagliardi, E Giuliano, E Venkateswararao… - Frontiers in …, 2021 - frontiersin.org
Advances in nanotechnology have favored the development of novel colloidal formulations
able to modulate the pharmacological and biopharmaceutical properties of drugs. The …

Interactions between nanoparticle-based food additives and other food ingredients: A review of current knowledge

M Moradi, R Razavi, AK Omer, A Farhangfar… - Trends in food science & …, 2022 - Elsevier
Background Nanomaterials are being explored in the food and agricultural industries for
their potential applications in improving the safety, quality, health, and sustainability of the …

Engineering exosome polymer hybrids by atom transfer radical polymerization

S Lathwal, SS Yerneni, S Boye… - Proceedings of the …, 2021 - National Acad Sciences
Exosomes are emerging as ideal drug delivery vehicles due to their biological origin and
ability to transfer cargo between cells. However, rapid clearance of exogenous exosomes …

Coating matters: Review on colloidal stability of nanoparticles with biocompatible coatings in biological media, living cells and organisms

J Schubert, M Chanana - Current medicinal chemistry, 2018 - ingentaconnect.com
Within the last two decades, the field of nanomedicine has not developed as successfully as
has widely been hoped for. The main reason for this is the immense complexity of the …

Current advances in the development of novel polymeric nanoparticles for the treatment of neurodegenerative diseases

A Cano, E Sanchez-Lopez, M Ettcheto… - …, 2020 - Taylor & Francis
Effective intervention is essential to combat the coming epidemic of neurodegenerative (ND)
diseases. Nanomedicine can overcome restrictions of CNS delivery imposed by the blood …

Nano-enhanced immunotherapy: Targeting the immunosuppressive tumor microenvironment

Y Jin, Y Huang, H Ren, H Huang, C Lai, W Wang… - Biomaterials, 2024 - Elsevier
The tumor microenvironment (TME), which is mostly composed of tumor cells, immune cells,
signaling molecules, stromal tissue, and the vascular system, is an integrated system that is …

Molecular engineering solutions for therapeutic peptide delivery

H Acar, JM Ting, S Srivastava, JL LaBelle… - Chemical Society …, 2017 - pubs.rsc.org
Proteins and their interactions in and out of cells must be well-orchestrated for the healthy
functioning and regulation of the body. Even the slightest disharmony can cause diseases …

Studying polymer surfaces and interfaces with sum frequency generation vibrational spectroscopy

X Lu, C Zhang, N Ulrich, M Xiao, YH Ma… - Analytical …, 2017 - ACS Publications
Usually a surface or an interface is well-defined with little diffusion from one side of the
surface or interface to the other, with the length scale being on the order of one to several …

Functionalized nanoparticles targeting tumor-associated macrophages as cancer therapy

Y He, RF de Araújo Júnior, LJ Cruz, C Eich - Pharmaceutics, 2021 - mdpi.com
The tumor microenvironment (TME) plays a central role in regulating antitumor immune
responses. As an important part of the TME, alternatively activated type 2 (M2) macrophages …

[HTML][HTML] Black TiO2 nanoprobe-mediated mild phototherapy reduces intracellular lipid levels in atherosclerotic foam cells via cholesterol regulation pathways instead …

T Dai, W He, S Tu, J Han, B Yuan, C Yao, W Ren… - Bioactive Materials, 2022 - Elsevier
Given that apoptosis increases the risk of plaque rupture, strategies that reduce intracellular
lipid levels without killing foam cells are warranted for safe and effective treatment of …