Modulating ROS to overcome multidrug resistance in cancer
The successful treatment of cancer has significantly improved as a result of targeted therapy
and immunotherapy. However, during chemotherapy, cancer cells evolve and can acquire …
and immunotherapy. However, during chemotherapy, cancer cells evolve and can acquire …
Mechanisms of cancer cell death induction by paclitaxel: an updated review
S Zhao, Y Tang, R Wang, M Najafi - Apoptosis, 2022 - Springer
Chemoresistance of cancer cells is a major problem in treating cancer. Knowledge of how
cancer cells may die or resist cancer drugs is critical to providing certain strategies to …
cancer cells may die or resist cancer drugs is critical to providing certain strategies to …
Systemic depletion of L-cyst(e)ine with cyst(e)inase increases reactive oxygen species and suppresses tumor growth
Cancer cells experience higher oxidative stress from reactive oxygen species (ROS) than do
non-malignant cells because of genetic alterations and abnormal growth; as a result …
non-malignant cells because of genetic alterations and abnormal growth; as a result …
[HTML][HTML] European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)
Abstract The European Cooperation in Science and Technology (COST) provides an ideal
framework to establish multi-disciplinary research networks. COST Action BM1203 (EU …
framework to establish multi-disciplinary research networks. COST Action BM1203 (EU …
Reactive oxygen species and cancer: A complex interaction
Abstract Elevated levels of Reactive Oxygen Species (ROS), increased antioxidant ability
and the maintenance of redox homeostasis can cumulatively contribute to tumor progression …
and the maintenance of redox homeostasis can cumulatively contribute to tumor progression …
NADPH oxidases and cancer
K Roy, Y Wu, JL Meitzler, A Juhasz, H Liu… - Clinical …, 2015 - portlandpress.com
The mechanism by which reactive oxygen species (ROS) are produced by tumour cells
remained incompletely understood until the discovery over the last 15 years of the family of …
remained incompletely understood until the discovery over the last 15 years of the family of …
[HTML][HTML] Methylsulfonylmethane: applications and safety of a novel dietary supplement
M Butawan, RL Benjamin, RJ Bloomer - Nutrients, 2017 - mdpi.com
Methylsulfonylmethane (MSM) has become a popular dietary supplement used for a variety
of purposes, including its most common use as an anti-inflammatory agent. It has been well …
of purposes, including its most common use as an anti-inflammatory agent. It has been well …
[HTML][HTML] Redox-mediated mechanism of chemoresistance in cancer cells
EK Kim, MG Jang, MJ Song, D Kim, Y Kim, HH Jang - Antioxidants, 2019 - mdpi.com
Cellular reactive oxygen species (ROS) status is stabilized by a balance of ROS generation
and elimination called redox homeostasis. ROS is increased by activation of endoplasmic …
and elimination called redox homeostasis. ROS is increased by activation of endoplasmic …
[HTML][HTML] Metabolic regulation of redox balance in cancer
V Purohit, DM Simeone, CA Lyssiotis - Cancers, 2019 - mdpi.com
Reactive oxygen species (ROS) are chemically active free radicals produced by partial
reduction of oxygen that can activate discrete signaling pathways or disrupt redox …
reduction of oxygen that can activate discrete signaling pathways or disrupt redox …
[HTML][HTML] The role of JNK in prostate cancer progression and therapeutic strategies
R Xu, J Hu - Biomedicine & Pharmacotherapy, 2020 - Elsevier
Prostate cancer (PC), which has high morbidity and mortality among elderly men, is
becoming the most common malignancy in men. The progression of PC is associated with …
becoming the most common malignancy in men. The progression of PC is associated with …