Global burden of sleep‐disordered breathing and its implications

MM Lyons, NY Bhatt, AI Pack, UJ Magalang - Respirology, 2020 - Wiley Online Library
One‐seventh of the world's adult population, or approximately one billion people, are
estimated to have OSA. Over the past four decades, obesity, the main risk factor for OSA, has …

Clarifying the role of sleep in depression: A narrative review

SR Pandi-Perumal, JM Monti, D Burman… - Psychiatry …, 2020 - Elsevier
It has been established that 4.4 to 20% of the general population suffers from a major
depressive disorder (MDD), which is frequently associated with a dysregulation of normal …

[HTML][HTML] Obstructive sleep apnea and inflammation: proof of concept based on two illustrative cytokines

L Kheirandish-Gozal, D Gozal - International journal of molecular …, 2019 - mdpi.com
Obstructive sleep apnea syndrome (OSAS) is a markedly prevalent condition across the
lifespan, particularly in overweight and obese individuals, which has been associated with …

Cannabinoid therapies in the management of sleep disorders: a systematic review of preclinical and clinical studies

AS Suraev, NS Marshall, R Vandrey, D McCartney… - Sleep medicine …, 2020 - Elsevier
Cannabinoids, including the two main phytocannabinoids Δ 9-tetrahydrocannabinol (THC)
and cannabidiol (CBD), are being increasingly utilised as pharmacological interventions for …

Artificial intelligence in psychiatry research, diagnosis, and therapy

J Sun, QX Dong, SW Wang, YB Zheng, XX Liu… - Asian Journal of …, 2023 - Elsevier
Psychiatric disorders are now responsible for the largest proportion of the global burden of
disease, and even more challenges have been seen during the COVID-19 pandemic …

Obstructive sleep apnea: transition from pathophysiology to an integrative disease model

WT McNicholas, D Pevernagie - Journal of Sleep Research, 2022 - Wiley Online Library
Obstructive sleep apnea (OSA) is characterised by recurring episodes of upper airway
obstruction during sleep and the fundamental abnormality reflects the inability of the upper …

Phenotypic subtypes of OSA: a challenge and opportunity for precision medicine

A Zinchuk, HK Yaggi - Chest, 2020 - Elsevier
Current strategies for the management of OSA reflect a one-size-fits-all approach. Diagnosis
and severity of OSA are based on the apnea-hypopnea index and treatment initiated with …

Obstructive sleep apnea treatment in adults

HP Chang, YF Chen, JK Du - The Kaohsiung journal of medical …, 2020 - Wiley Online Library
Sleep‐related breathing disorders are complex problems that decrease quality of life and
increase morbidity and mortality in patients. Comprehensive evaluation is essential for …

Adherence to CPAP: what should we be aiming for, and how can we get there?

JP Bakker, TE Weaver, S Parthasarathy, MS Aloia - Chest, 2019 - Elsevier
The purpose of this review was to summarize what is currently known regarding two
important questions facing the field of sleep medicine today:(1) How many hours of CPAP …

More than the sum of the respiratory events: personalized medicine approaches for obstructive sleep apnea

BA Edwards, S Redline, SA Sands… - American journal of …, 2019 - atsjournals.org
Traditionally, the presence and severity of obstructive sleep apnea (OSA) have been defined
by the apnea–hypopnea index (AHI). Continuous positive airway pressure is generally first …