During the first half of 2022, the World Health Organization reported an outbreak of acute
severe hepatitis of unknown aetiology (AS-Hep-UA) in children, following initial alerts from …

In October 2021, a case of acute hepatic failure without any known cause was identified in
the United States of America. Upon further investigation, other children aged 1–6 years were …

Hepatitis is defined as the inflammatory reaction of the liver parenchyma. It is either acute,
which resolves within six months or may be chronic. An outbreak of severe, acute hepatitis of …

Acute hepatitis has always been a public health concern, but the recent clustering of cases
in various parts of the world has drawn some special attention. The sudden rise in cases has …

Severe cases of acute hepatitis have been reported all around the world since 5 April 2022.
Common viral hepatitis agents (HAV, HBV, HCV, HDV, and HEV) were ruled out by …

Abstract Background Acute Severe Hepatitis of Unknown Etiology (ASHUE) emerged as a
new global outbreak in Indonesia early May 2022, coinciding with the COVID-19 pandemic …

The emergence of acute, severe non hepA–E hepatitis of unknown etiology (ASHUE) has
attracted global concern owing to the very young age of the patients and its unknown …

Clusters of acute non HepA-E hepatitis cases in previously healthy children have been
reported globally. At least, 1010 cases were identified in 35 countries, 5% of those cases …

Coinfection with human adenovirus (HAdV) and SARS-CoV-2 has been associated with
acute hepatitis in children with unknown etiology. Similar cases have been reported in many …

Abstract Background Since October 2021, multiple paediatric cases of severe acute hepatitis
of unknown aetiology (SAHUA) not caused by hepatitis A–E viruses have been reported by …