Cardiac valve replacement, albeit a well-established and safe procedure, is associated with
a significant risk of complications. Symptomatic paravalvular leak (PVL) is a significant post …

The incidence of paravalvular leaks after surgical valve replacement is estimated to be 2-
17%. Paravalvular leaks (PVL) can be asymptomatic and not require treatment or can cause …

McElhinney Development and Approval of Small-Market Devices 3 on the location of the
defect relative to the prosthesis, devices implanted to close a PVL often protrude in one …

OBJECTIVES We aimed to analyse the pathology of paravalvular leak (PVL), and determine
the long-term outcomes of redo mitral valve replacement and risk factors of all-cause …

Introduction and objectives Percutaneous closure of paravalvular leakage is an alternative
to surgery in high-risk patients, but its use has been limited by a lack of specific devices …

A critically ill patient had a major mitral paravalvular leak, failed device closure of the leak,
and severe hemolytic anemia after a third mitral valve replacement. Echocardiography …

Reoperation of patients with perivalvular leaks due to heart failure or hemolysis is
associated with increased morbidity and mortality. Percutaneous closure using an Amplatzer …

Background This study sought to compare various outcomes among a new specifically
designed transcatheter paravalvular leak closure (TPVLC) device and the devices that are …

This study aims at achieving a proof-of-concept for a novel device designed to occlude the
orifices that may form between transcatheter valves and host tissues after TAVI. The device …

Objectives: This study sought to describe and compare a novel fluoroscopic method and a 2-
dimensional transesophageal echocardiographic (TEE) method to localize mitral …