Abstract Progesterone Receptor Membrane Component 1 (PGRMC1) is a heme-binding
protein that has been implicated in a wide range of cell and tissue functions, including …

Progesterone and its synthetic analogues, progestins, participate in the regulation of cell
differentiation, proliferation and cell cycle progression. Progestins are usually applied for …

Progesterone Receptor Membrane Component 1 (PGRMC1) is a tumour-promoting factor in
several types of cancer but its role in brain tumours is poorly characterized thus far. Our …

Cancer cells usually show different metabolic patterns compared with healthy cells due to
the reprogramming of metabolic processes. The process of lipid metabolism undergoes …

Progesterone receptor membrane component (PGRMC) proteins play important roles in
tumor growth, progression, and chemoresistance, of which PGRMC1 is the best …

Simple Summary Progesterone receptor membrane component 1 (PGRMC1) and epidermal
growth factor receptor (EGFR) are highly expressed in various cancers. Here, we first …

Lung cancer (LC) is one of the most incident malignancies and a leading cause of cancer
mortality worldwide. Common tumorigenic drivers of LC mainly include genetic alterations of …

Cancer stem cells (CSCs) are responsible for tumor chemoresistance, and the aryl
hydrocarbon receptor (AHR) is indispensable for maintaining CSC characteristics. Here, we …

Cancer seriously endangers human health. Gastrointestinal cancer is the most common and
major malignant tumor, and its morbidity and mortality are gradually increasing. Although …

Heterotopic ossification (HO) is the formation of abnormal mature lamellar bone in extra-
skeletal sites, including soft tissues and joints, which result in high rates of disability. The …