Metabolomics: small molecules that matter more

BC Muthubharathi, T Gowripriya, K Balamurugan - Molecular omics, 2021 - pubs.rsc.org
Metabolomics, an analytical study with high-throughput profiling, helps to understand
interactions within a biological system. Small molecules, called metabolites or metabolomes …

Metabolomics in rheumatoid arthritis: Advances and review

L Xu, C Chang, P Jiang, K Wei, R Zhang, Y Jin… - Frontiers in …, 2022 - frontiersin.org
Rheumatoid arthritis (RA) is an autoimmune disease accompanied by metabolic alterations.
The metabolic profiles of patients with RA can be determined using targeted and non …

Serum metabolomic and lipidomic profiling identifies diagnostic biomarkers for seropositive and seronegative rheumatoid arthritis patients

H Luan, W Gu, H Li, Z Wang, L Lu, M Ke, J Lu… - Journal of translational …, 2021 - Springer
Background Diagnosing seronegative rheumatoid arthritis (RA) can be challenging due to
complex diagnostic criteria. We sought to discover diagnostic biomarkers for seronegative …

Zinc and cadmium in the aetiology and pathogenesis of osteoarthritis and rheumatoid arthritis

T Frangos, W Maret - Nutrients, 2020 - mdpi.com
Osteoarthritis (OA) and rheumatoid arthritis (RA) are inflammatory articular conditions with
different aetiology, but both result in joint damage. The nutritionally essential metal zinc …

A review of metabolomic profiling in rheumatoid arthritis: bringing new insights in disease pathogenesis, treatment and comorbidities

BJ Bartikoski, MS De Oliveira, RC do Espírito Santo… - Metabolites, 2022 - mdpi.com
Metabolomic analysis provides a wealth of information that can be predictive of distinctive
phenotypes of pathogenic processes and has been applied to better understand disease …

Non-invasive metabolic biomarkers for early diagnosis of diabetic nephropathy: Meta-analysis of profiling metabolomics studies

A Roointan, Y Gheisari, KL Hudkins… - Nutrition, Metabolism and …, 2021 - Elsevier
Aim Diabetic nephropathy (DN) is one of the worst complications of diabetes. Despite a
growing number of DN metabolite profiling studies, most studies are suffering from …

Metabolomics of synovial fluid and infrapatellar fat pad in patients with osteoarthritis or rheumatoid arthritis

P Nieminen, W Hämäläinen, J Savinainen, M Lehtonen… - Inflammation, 2022 - Springer
Osteoarthritis (OA) and autoimmune-driven rheumatoid arthritis (RA) are inflammatory joint
diseases with complex and insufficiently understood pathogeneses. Our objective was to …

Caution in studying and interpreting the lupus metabolome

T Zhang, C Mohan - Arthritis research & therapy, 2020 - Springer
Several metabolomics studies have shed substantial light on the pathophysiological
pathways underlying multiple diseases including systemic lupus erythematosus (SLE). This …

Therapeutic effects of columbianadin from Angelicae Pubescentis radix on the progression of collagen-induced rheumatoid arthritis by regulating inflammation and …

S Chen, Y Wang, L Zhang, Y Han, C Liang… - Journal of …, 2023 - Elsevier
Ethnopharmacological relevance Angelicae pubescentis radix (APR) has a long history in
the treatment of rheumatoid arthritis (RA) in China. It has the effects of dispelling wind to …

Potential clinical biomarkers in rheumatoid arthritis with an omic approach

Y Puentes-Osorio, P Amariles, MÁ Calleja… - Autoimmunity …, 2021 - Springer
Objective To aid in the selection of the most suitable therapeutic option in patients with
diagnosis of rheumatoid arthritis according to the phase of disease, through the review of …