Frailty is a decline in functional reserve across multiple physiological systems. A key
component of frailty is sarcopenia, which denotes a loss of skeletal muscle mass and …

In adults, more deficits in physical than mental health domains are found in survivors of AKI
in critical care, whereas memory deficits and learning impairments have been noted in …

Purpose We aimed to study the prevalence of frailty, evaluate risk factors, and understand
impact on outcomes in India. Methods This was a prospective registry-embedded cohort …

Defects in the DNA damage response and repair (DDR/R) network accumulate during the
aging process. Physical frailty, a state of reduced physiological function and decreased …

Aim To evaluate the association between frailty and post-cardiac arrest survival, functional
decline, and cognitive decline, among patients receiving home care. Methods Frailty was …

Purpose Frailty is common in critically ill patients but the timing and optimal method of frailty
ascertainment, trajectory and relationship with care processes remain uncertain. We sought …

Background Understanding how health trajectories are related to the likelihood of adverse
outcomes and healthcare utilization is key to planning effective strategies for improving …

Background The relationship between body mass index (BMI) and outcomes in the acute
care setting is controversial, with evidence suggesting that obesity is either protective-which …

Background Skeletal muscle loss is associated with adverse outcomes in critically ill patients
and risk factors of acute skeletal muscle loss are not well described. This study aims to …

Introduction Rises in average life expectancy, increased comorbidities and frailty among
older patients lead to higher admission rates to intensive care units (ICU). During an ICU …